alpha Tubulin Antibody (A-6): sc-398103

α Tubulin Antibody (A-6) is a mouse monoclonal IgG2b antibody that targets α Tubulin, a fundamental protein in the cytoskeleton, derived from human origin. Raised against an epitope located between amino acids 22-49 of the N-terminal region of α Tubulin, α Tubulin (A-6) antibody is recommended for use in western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). α Tubulin is crucial for the formation of microtubules, which are dynamic structures that play a pivotal role in maintaining cell shape, facilitating intracellular transport, and segregating chromosomes during cell division. α Tubulin functions by forming heterodimers with β Tubulin, which then polymerize into microtubules that are essential for mitosis, cell signaling, and cellular movement. Additionally, α Tubulin undergoes post-translational modifications, such as tyrosination and detyrosination, which regulate interactions with microtubule-associated proteins (MAPs) and motor proteins like kinesin and dynein, influencing the stability and dynamics of microtubules. Known by alternate names such as Tubulin alpha chain or TUBA, α Tubulin is involved in important cellular processes such as cilia and flagella formation, as well as in the proper function of the centrosome during cell division. anti-α Tubulin antibody (A-6) is highly cross-reactive, recognizing α Tubulin in a wide range of species, including mouse, rat, human, avian, equine, canine, bovine, and porcine, making α Tubulin (A-6) monoclonal antibody a versatile tool for studying microtubule function across various biological systems. α Tubulin (A-6) antibody provides valuable insights into the structure and function of microtubules, their post-translational regulation, and their role in cellular architecture.

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Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-alpha Tubulin Antibody (A-6) has 69 citations in a variety of scientific publications.

Primary antibodies like Anti-alpha Tubulin Antibody (A-6) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

alpha Tubulin Antibody (A-6) Specifications

Alternate Product Name: α Tubulin

Product Clone Name: A-6

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG_2b kappa light chain

Amino Acids: 22-49

Epitope Target: α Tubulin

Epitope Species: human

Product Reactivity/Detection: α Tubulin

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: equine, canine, bovine, porcine and avian

Additional Non-Mammalian Reactivity: avian

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 200 µg IgG_2b kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 69 citations in various scientific publications

Available Conjugates/Forms for alpha Tubulin Antibody (A-6): AC: Agarose, AF488: Alexa Fluor^® 488, AF546: Alexa Fluor^® 546, AF594: Alexa Fluor^® 594, AF647: Alexa Fluor^® 647, AF680: Alexa Fluor^® 680, AF790: Alexa Fluor^® 790, FITC: Fluoroscein, HRP: Horseradish Peroxidase, P: Blocking Peptide, PE: Phycoerythrin

The preferred alpha Tubulin antibody is alpha Tubulin Antibody (TU-02): sc-8035.