α-S1-casein Antibody (D-10): sc-373711

α-S1-casein Antibody (D-10) is a mouse monoclonal IgG1 antibody that detects α-S1-casein in mouse samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). α-S1-casein, also known as CSN1S1, CSN1, or CASA, is a 185 amino acid secreted protein specific to the mammary gland and is a member of the α-casein family. α-S1-casein plays a crucial role in calcium phosphate transport, essential for the development and maintenance of healthy bones and teeth. α-S1-casein forms a disulfide-linked heterodimer with κ-casein, enhancing functionality in milk and allowing effective mineral transport. α-S1-casein exists in multiple alternatively spliced isoforms, which may contribute to diverse biological functions. The gene encoding α-S1-casein is located on human chromosome 4, a region containing other casein family members and housing nearly 6% of the human genome, including some of the largest gene deserts. Understanding α-S1-casein structure and function is vital, as defects in genes on chromosome 4 are linked to various genetic disorders, highlighting α-S1-casein importance in both health and disease.

The preferred α-S1-casein antibody is α-S1-casein Antibody (D-8): sc-376961.