Aciculin Antibody (F-2): sc-365419

Aciculin Antibody (F-2) is a mouse monoclonal IgG2b antibody that detects Aciculin in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Aciculin, also known as PGM5 (phosphoglucomutase 5) or PGMRP, is a 567 amino acid protein that plays a crucial role in the interconversion of glucose-1-phosphate and glucose-6-phosphate, which is vital for cellular energy metabolism and glycogen synthesis. Aciculin is localized at cell junctions and is predominantly expressed in smooth and cardiac muscle, where Aciculin binds magnesium as a cofactor and interacts with dystrophin and utrophin, suggesting involvement in maintaining cytoskeletal integrity and function. Aciculin exists in two alternatively spliced isoforms and is encoded by a gene located on human chromosome 9, a region that contains over 900 genes and accounts for nearly 4% of the human genome. The ability of anti-Aciculin antibody (F-2) to interact with key cytoskeletal proteins highlights Aciculin′s importance in muscle function and cellular architecture, making anti-Aciculin antibody (F-2) an essential tool for researchers studying muscle physiology and related disorders.

The preferred Aciculin antibody is Aciculin Antibody (14F8): sc-73613.