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ACAD-11 Antibody (C-7): sc-514357

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Datasheets
  • ACAD-11 Antibody (C-7) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 208-229 within an internal region of ACAD-11 of human origin
  • recommended for detection of ACAD-11 of mouse, rat and human origin by WB, IP, IF and ELISA
  • m-IgG Fc BP-HRP, m-IgG2a BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ACAD-11 Antibody (C-7) for WB applications. These reagents are now offered in bundles with ACAD-11 Antibody (C-7) (see ordering information below).
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    ACAD-11 Antibody (C-7) is a mouse monoclonal IgG2a antibody that detects acyl-Coenzyme A dehydrogenase family member 11 (ACAD-11) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACAD-11 plays a crucial role in the metabolism of fatty acids and amino acids, serving as a vital source of energy for the heart and skeletal muscle, which is essential for maintaining cellular function and overall energy homeostasis. ACAD-11 is located primarily in the mitochondria, where ACAD-11 catalyzes the first step in the fatty acid oxidation pathway, converting acyl-CoA substrates into trans-2-enoyl-CoA. This mitochondrial localization ensures efficient fatty acid processing for energy production, particularly during periods of fasting or increased energy demand. Dysregulation of ACAD-11 can lead to metabolic disorders, highlighting its importance in both normal physiology and disease states. ACAD-11 (C-7) antibody serves as an invaluable tool for researchers studying metabolic pathways and related disorders, providing reliable detection and characterization of ACAD-11.

    For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

    Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA

    LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences

    ACAD-11 Antibody (C-7) References:

    1. Acyl-CoA dehydrogenases: Dynamic history of protein family evolution.  |  Swigonová, Z., et al. 2009. J Mol Evol. 69: 176-93. PMID: 19639238
    2. Identification and characterization of new long chain acyl-CoA dehydrogenases.  |  He, M., et al. 2011. Mol Genet Metab. 102: 418-29. PMID: 21237683
    3. An evaluation of the effects of Lactobacillus ingluviei on body weight, the intestinal microbiome and metabolism in mice.  |  Angelakis, E., et al. 2012. Microb Pathog. 52: 61-8. PMID: 22020311
    4. Transcriptional Response of Subcutaneous White Adipose Tissue to Acute Cold Exposure in Mice.  |  Liang, X., et al. 2019. Int J Mol Sci. 20: PMID: 31443159
    5. Identification of novel genes by targeted exome sequencing in Retinoblastoma.  |  Bisht, S., et al. 2022. Ophthalmic Genet. 43: 771-788. PMID: 35930312
    6. Isolation of Mammalian Peroxisomes by Density Gradient Centrifugation.  |  Manner, A. and Islinger, M. 2023. Methods Mol Biol. 2643: 1-12. PMID: 36952174
    7. Establishment and validation of a novel peroxisome-related gene prognostic risk model in kidney clear cell carcinoma.  |  Zhang, J., et al. 2024. BMC Urol. 24: 26. PMID: 38297313
    8. Development and experimental validation of an energy metabolism-related gene signature for diagnosing of osteoporosis.  |  Lu, Y., et al. 2024. Sci Rep. 14: 8153. PMID: 38589566
    9. Structural basis for expanded substrate specificities of human long chain acyl-CoA dehydrogenase and related acyl-CoA dehydrogenases.  |  Narayanan, B., et al. 2024. Sci Rep. 14: 12976. PMID: 38839792
    10. Tangzhiping Decoction Improves Glucose and Lipid Metabolism and Exerts Protective Effects Against White Adipose Tissue Dysfunction in Prediabetic Mice.  |  Wang, C., et al. 2024. Drug Des Devel Ther. 18: 2951-2969. PMID: 39050798

    Ordering Information

    Product NameCatalog #UNITPriceQtyFAVORITES

    ACAD-11 Antibody (C-7)

    sc-514357
    200 µg/ml
    $322.00

    ACAD-11 Antibody (C-7): m-IgG Fc BP-HRP Bundle

    sc-538630
    200 µg Ab; 10 µg BP
    $361.00

    ACAD-11 Antibody (C-7): m-IgGκ BP-HRP Bundle

    sc-536276
    200 µg Ab; 40 µg BP
    $361.00

    ACAD-11 Antibody (C-7): m-IgG2a BP-HRP Bundle

    sc-548359
    200 µg Ab; 10 µg BP
    $361.00

    ACAD-11 (C-7) Neutralizing Peptide

    sc-514357 P
    100 µg/0.5 ml
    $69.00

    What application is the blocking peptide sc-514357 P appropriate for?

    Asked by: jerojero
    Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
    Answered by: Technical Support
    Date published: 2017-03-01
    • y_2026, m_4, d_10, h_11CST
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    Rated 5 out of 5 by from Great Western blot data of ACADGreat Western blot data of ACAD-11 expression in non-transfected and mouse ACAD-11 transfected 293T whole cell lysates. -SCBT QC
    Date published: 2013-05-13
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    ACAD-11 Antibody (C-7) is rated 5.0 out of 5 by 1.
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