ACAA1 Antibody (C-8): sc-514051
- ACAA1 Antibody (C-8) is a mouse monoclonal IgG2b κ ACAA1 antibody, cited in 1 publications, provided at 200 µg/ml
- specific for an epitope mapping between amino acids 7-27 near the N-terminus of ACAA1 of human origin
- ACAA1 Antibody (C-8) is recommended for detection of ACAA1 of mouse, rat and human origin by WB, IP, IF and ELISA
- Anti-ACAA1 Antibody (C-8) is available conjugated to agarose for IP; HRP for WB, IHC(P) and ELISA; and to either phycoerythrin or FITC for IF, IHC(P) and FCM
- also available conjugated to Alexa Fluor® 488, Alexa Fluor® 546, Alexa Fluor® 594 or Alexa Fluor® 647 for WB (RGB), IF, IHC(P) and FCM, and for use with RGB fluorescent imaging systems, such as iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- also available conjugated to Alexa Fluor® 680 or Alexa Fluor® 790 for WB (NIR), IF and FCM; for use with Near-Infrared (NIR) detection systems, such as LI-COR®Odyssey®, iBright™ FL1000, FluorChem™, Typhoon, Azure and other comparable systems
- m-IgG Fc BP-HRP, m-IgG2b BP-HRP and m-IgGκ BP-HRP are the preferred secondary detection reagents for ACAA1 Antibody (C-8) for WB applications. These reagents are now offered in bundles with ACAA1 Antibody (C-8) (see ordering information below).
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ACAA1 Antibody (C-8) is a mouse monoclonal IgG2b kappa light chain antibody that detects ACAA1 protein of mouse, rat, and human origin by western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). ACAA1 (C-8) antibody is available in both non-conjugated and various conjugated forms, including agarose, horseradish peroxidase (HRP), phycoerythrin (PE), fluorescein isothiocyanate (FITC), and multiple Alexa Fluor® conjugates. ACAA1 protein, also known as acetyl-Coenzyme A acyltransferase 1 or Peroxisomal 3-oxoacyl-CoA thiolase, plays a crucial role in lipid metabolism, specifically in the fatty acid oxidation pathway. This 424 amino acid enzyme is localized in the peroxisome, where ACAA1 catalyzes the conversion of acyl-CoA and acetyl-CoA to 3-oxoacyl-CoA, a vital step in breaking down fatty acids for energy production. ACAA1 exhibits high enzymatic activity in key tissues such as the liver, kidney, intestine, and white adipose tissue, where ACAA1 exists in two isoforms, type A and type B. Notably, human ACAA1 shares 86% amino acid identity with its rat counterpart, indicating a conserved function across species, which underscores ACAA1′s importance in metabolic processes. Anti-ACAA1 antibody (C-8) in various forms allows for versatile applications in research, enabling scientists to explore the intricate roles of ACAA1 in health and disease.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
ACAA1 Antibody (C-8) References:
- Molecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genes. | Chevillard, G., et al. 2004. BMC Biochem. 5: 3. PMID: 15043762
- A novel, cleavable peroxisomal targeting signal at the amino-terminus of the rat 3-ketoacyl-CoA thiolase. | Swinkels, BW., et al. 1991. EMBO J. 10: 3255-62. PMID: 1680677
- Cloning and sequence determination of cDNA encoding a second rat liver peroxisomal 3-ketoacyl-CoA thiolase. | Bodnar, AG. and Rachubinski, RA. 1990. Gene. 91: 193-9. PMID: 2210380
- Rat peroxisomal 3-ketoacyl-CoA thiolase gene. Occurrence of two closely related but differentially regulated genes. | Hijikata, M., et al. 1990. J Biol Chem. 265: 4600-6. PMID: 2307679
- Structural analysis of cDNA for rat peroxisomal 3-ketoacyl-CoA thiolase. | Hijikata, M., et al. 1987. J Biol Chem. 262: 8151-8. PMID: 3036803
- Properties of peroxisomal 3-ketoacyl-coA thiolase from rat liver. | Miyazawa, S., et al. 1981. J Biochem. 90: 511-9. PMID: 6117552
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
ACAA1 Antibody (C-8) | sc-514051 | 200 µg/ml | $322.00 | |||
ACAA1 Antibody (C-8): m-IgG Fc BP-HRP Bundle | sc-531015 | 200 µg Ab; 10 µg BP | $361.00 | |||
ACAA1 Antibody (C-8): m-IgGκ BP-HRP Bundle | sc-524588 | 200 µg Ab, 40 µg BP | $361.00 | |||
ACAA1 Antibody (C-8): m-IgG2b BP-HRP Bundle | sc-550251 | 200 µg Ab; 10 µg BP | $361.00 | |||
ACAA1 Antibody (C-8) AC | sc-514051 AC | 500 µg/ml, 25% agarose | $424.00 | |||
ACAA1 Antibody (C-8) HRP | sc-514051 HRP | 200 µg/ml | $322.00 | |||
ACAA1 Antibody (C-8) FITC | sc-514051 FITC | 200 µg/ml | $336.00 | |||
ACAA1 Antibody (C-8) PE | sc-514051 PE | 200 µg/ml | $349.00 | |||
ACAA1 Antibody (C-8) Alexa Fluor® 488 | sc-514051 AF488 | 200 µg/ml | $364.00 | |||
ACAA1 Antibody (C-8) Alexa Fluor® 546 | sc-514051 AF546 | 200 µg/ml | $364.00 | |||
ACAA1 Antibody (C-8) Alexa Fluor® 594 | sc-514051 AF594 | 200 µg/ml | $364.00 | |||
ACAA1 Antibody (C-8) Alexa Fluor® 647 | sc-514051 AF647 | 200 µg/ml | $364.00 | |||
ACAA1 Antibody (C-8) Alexa Fluor® 680 | sc-514051 AF680 | 200 µg/ml | $364.00 | |||
ACAA1 Antibody (C-8) Alexa Fluor® 790 | sc-514051 AF790 | 200 µg/ml | $364.00 | |||
ACAA1 (C-8) Neutralizing Peptide | sc-514051 P | 100 µg/0.5 ml | $69.00 |