Date published: 2026-4-24

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2-(Methyldiphenylsilyl)ethanol (CAS 40438-48-0)

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Alternate Names:
(2-Hydroxyethyl)diphenylmethylsilane; 2-(Diphenylmethylsilyl)ethanol
Application:
2-(Methyldiphenylsilyl)ethanol is a protecting group for internucleotidic phosphates in oligonucleotide synthesis
CAS Number:
40438-48-0
Purity:
99%
Molecular Weight:
242.39
Molecular Formula:
C15H18OSi
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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2-(Methyldiphenylsilyl)ethanol is a silicon-based organic compound that is of particular interest in the field of organosilicon chemistry. Its applications in research are diverse, encompassing the synthesis of silicon-containing polymers and the modification of organic molecules with silyl groups, which can alter solubility, reactivity, and stability. As a silylating agent, it is used to protect hydroxyl groups during complex organic syntheses, where selective deprotection is often required. The compound′s diphenylsilyl moiety can also be instrumental in studies probing the steric and electronic effects of substituents on silicon atoms. Moreover, 2-(Methyldiphenylsilyl)ethanol is relevant in materials science for the preparation of surfaces with specific chemical functionalities, potentially impacting the fields of coatings and adhesives.


2-(Methyldiphenylsilyl)ethanol (CAS 40438-48-0) References

  1. Synthesis and biochemical evaluation of phosphonoformate oligodeoxyribonucleotides.  |  Yamada, CM., et al. 2006. J Am Chem Soc. 128: 5251-61. PMID: 16608361

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

2-(Methyldiphenylsilyl)ethanol, 5 g

sc-237873
5 g
$226.00