Date published: 2026-7-21

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Prolyl Hydroxylase Antibodies

Santa Cruz Biotechnology delivers a wide array of Prolyl Hydroxylase monoclonal antibodies for investigating prolyl hydroxylases in various biological processes. Prolyl Hydroxylase Antibodies are optimized for techniques such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Prolyl hydroxylases are essential enzymes involved in the post-translational modification of proteins, particularly in the hydroxylation of proline residues in collagen and other proteins. The hydroxylation process is fundamental for collagen stability and function, impacting wound healing, tissue repair, and cellular responses to hypoxia. Prolyl hydroxylases have emerged as significant factors in various physiological and pathological conditions, including fibrosis and cancer. Researchers can utilize specific monoclonal antibodies to examine the expression, localization, and interactions of prolyl hydroxylases across different experimental conditions. Understanding prolyl hydroxylase activity and regulation can provide valuable insights into disease mechanisms and potential therapeutic strategies. The extensive selection of monoclonal antibodies from Santa Cruz Biotechnology enables researchers worldwide to advance scientific understanding of prolyl hydroxylases and their impact on human health.

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Prolyl Hydroxylase Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HIF PHD1 Antibody (2G3)

sc-293220mouse IgG2a κFL (h)WB, IP, IF, IHC(P), ELISAh
1
(1)

HIF PHD2 Antibody (H-8)

sc-271835mouse IgG1 κ240-288 (h)WB, IP, IF, ELISAm, r, h
20
(13)

HIF PHD3 Antibody (EG188e/d5)

sc-517601mouse IgG1 κ1-100 (h)WB, IP, IF, IHC(P)h

new

(2)

Prolyl Hydroxylase siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HIF PHD1 siRNA (h)

sc-45616hGene SilencingN/A
4
(0)

HIF PHD1 shRNA Plasmid (h)

sc-45616-SHhGene SilencingPuromycin
4
(0)

HIF PHD1 shRNA (h) Lentiviral Particles

sc-45616-VhGene SilencingPuromycin
4
(0)

HIF PHD1 siRNA (m)

sc-45617mGene SilencingN/A
1
(0)

HIF PHD1 shRNA Plasmid (m)

sc-45617-SHmGene SilencingPuromycin
1
(0)

HIF PHD1 shRNA (m) Lentiviral Particles

sc-45617-VmGene SilencingPuromycin
1
(0)

HIF PHD2 siRNA (h)

sc-45537hGene SilencingN/A
10
(0)

HIF PHD2 shRNA Plasmid (h)

sc-45537-SHhGene SilencingPuromycin
10
(0)

HIF PHD2 shRNA (h) Lentiviral Particles

sc-45537-VhGene SilencingPuromycin
10
(0)

HIF PHD2 siRNA (m)

sc-45538mGene SilencingN/A
1
(0)

HIF PHD2 shRNA Plasmid (m)

sc-45538-SHmGene SilencingPuromycin
1
(0)

HIF PHD2 shRNA (m) Lentiviral Particles

sc-45538-VmGene SilencingPuromycin
1
(0)

HIF PHD3 siRNA (h)

sc-45799hGene SilencingN/A
5
(0)

HIF PHD3 shRNA Plasmid (h)

sc-45799-SHhGene SilencingPuromycin
5
(0)

HIF PHD3 shRNA (h) Lentiviral Particles

sc-45799-VhGene SilencingPuromycin
5
(0)

HIF PHD3 siRNA (m)

sc-45800mGene SilencingN/A
2
(0)

HIF PHD3 shRNA Plasmid (m)

sc-45800-SHmGene SilencingPuromycin
2
(0)

HIF PHD3 shRNA (m) Lentiviral Particles

sc-45800-VmGene SilencingPuromycin
2
(0)

Prolyl Hydroxylase CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

HIF PHD1 CRISPR/Cas9 KO Plasmid (h2)

sc-402824-KO-2Gene Knockouth0
(0)

HIF PHD1 CRISPR/Cas9 KO Plasmid (m)

sc-431082Gene Knockoutm0
(0)

HIF PHD1 HDR Plasmid (m)

sc-431082-HDRHomology Directed Repairm0
(0)

HIF PHD2 CRISPR/Cas9 KO Plasmid (h)

sc-403334Gene Knockouth0
(0)

HIF PHD2 HDR Plasmid (h)

sc-403334-HDRHomology Directed Repairh0
(0)

HIF PHD2 CRISPR/Cas9 KO Plasmid (m)

sc-431081Gene Knockoutm0
(0)

HIF PHD2 HDR Plasmid (m)

sc-431081-HDRHomology Directed Repairm0
(0)

HIF PHD3 CRISPR/Cas9 KO Plasmid (h)

sc-403671Gene Knockouth0
(0)

Prolyl Hydroxylase CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

HIF PHD1 Double Nickase Plasmid (h)

sc-402824-NICGene Knockouth0
(0)

HIF PHD1 Double Nickase Plasmid (h2)

sc-402824-NIC-2Gene Knockouth0
(0)

HIF PHD2 Double Nickase Plasmid (h)

sc-403334-NICGene Knockouth0
(0)

HIF PHD2 Double Nickase Plasmid (h2)

sc-403334-NIC-2Gene Knockouth0
(0)

HIF PHD2 Double Nickase Plasmid (m)

sc-431081-NICGene Knockoutm0
(0)

HIF PHD3 Double Nickase Plasmid (m)

sc-431083-NICGene Knockoutm0
(0)

Prolyl Hydroxylase CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

HIF PHD2 CRISPR Activation Plasmid (h)

sc-403334-ACTGene Activationh0
(0)

HIF PHD3 CRISPR Activation Plasmid (h)

sc-403671-ACTGene Activationh0
(0)

HIF PHD3 CRISPR Activation Plasmid (h2)

sc-403671-ACT-2Gene Activationh0
(0)

HIF PHD3 Lentiviral Activation Particles (h)

sc-403671-LACGene Activationh0
(0)

HIF PHD3 Lentiviral Activation Particles (h2)

sc-403671-LAC-2Gene Activationh0
(0)

HIF PHD3 CRISPR Activation Plasmid (m2)

sc-431083-ACT-2Gene Activationm0
(0)

HIF PHD3 Lentiviral Activation Particles (m)

sc-431083-LACGene Activationm0
(0)

HIF PHD3 Lentiviral Activation Particles (m2)

sc-431083-LAC-2Gene Activationm0
(0)

PHD3 CRISPR Activation Plasmid (m)

sc-431083-ACTGene Activationm0
(0)