Date published: 2026-6-3

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MCM Antibodies

Santa Cruz Biotechnology features a diverse variety of MCM Antibodies for research in cell cycle regulation and DNA replication. MCM Antibodies are compatible with multiple techniques, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Minichromosome maintenance (MCM) proteins are essential components in the initiation of DNA replication, ensuring accurate duplication of genetic material during cell division. MCM protein function maintains genomic stability, while its dysregulation has been linked to various cancers and other diseases. Research focusing on MCM proteins reveals important insights into cellular proliferation and the mechanisms underlying tumorigenesis. Scientists can explore the complex relationship between MCM proteins and cell cycle checkpoints. Investigating MCM protein interactions helps uncover new therapeutic targets for cancer treatment. Understanding MCM protein regulation advances knowledge of DNA replication and repair mechanisms. Santa Cruz Biotechnology monoclonal MCM antibodies support researchers worldwide in advancing scientific discoveries and developing potential therapeutic strategies.

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MCM Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MCM2 Antibody (E-8)

sc-373702mouse IgG2b κ9-34 (h)WB, IP, IF, ELISAm, r, h
22
(13)

Mcm2 Antibody (C-3)

sc-515723mouse IgG2b κ11-34 (Saccharomyces cerevisiae)WB, IP, IF, ELISAS. cerevisiae

new

(2)

MCM3 Antibody (E-8)

sc-390480mouse IgG1 κ1-215 (h)WB, IP, IF, IHC(P), ELISAm, r, h
15
(15)

MCM3 Antibody (E-7)

sc-365616mouse IgG1 κ3-27 (h)WB, IP, IF, ELISAm, r, h
10
(4)

MCM4 Antibody (G-7)

sc-28317mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
27
(16)

MCM4 Antibody (C-10)

sc-48407mouse IgG1 κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
7
(4)

MCM5 Antibody (E-10)

sc-165994mouse IgG2b κ1-300 (h)WB, IP, IF, IHC(P), ELISAm, r, h
14
(10)

MCM5 Antibody (G-1)

sc-165995mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAm, r, h
7
(2)

MCM5 Antibody (C-10)

sc-165993mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAm, r, h
2
(2)

MCM6 Antibody (H-8)

sc-393618mouse IgG2a κ792-821 (h)WB, IP, IF, IHC(P), ELISAm, r, h
20
(13)

MCM6 Antibody (D-12)

sc-55577mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAm, r, h
4
(3)

MCM6 Antibody (B-4)

sc-55576mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAm, r, h
3
(2)

MCM6 Antibody (1)

sc-135983mouse IgG1670-792 (h)WB, IP, IFh

new

(1)

MCM6 Antibody (G-8)

sc-393463mouse IgG1 κ7-32 (h)WB, IP, IF, ELISAm, r, h

new

(2)

MCM7 Antibody (141.2)

sc-9966mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
194
(17)

MCM7 Antibody (DCS-141)

sc-65469mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
21
(8)

MCM7 Antibody (47DC141)

sc-56324mouse IgG1 κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h, Xenopus and canine
21
(4)

MCM7 Antibody (G-7)

sc-46687mouse IgG2a κ1-300 (h)WB, IP, IF, ELISAm, r, h
5
(5)

MCM7 Antibody (0.N.194)

sc-71550mouse IgG1 κFL (h)WB, IP, IF, IHC(P)m, r, h
3
(2)

MCM7 Antibody (H-5)

sc-374403mouse IgG2a κ673-709 (h)WB, IP, IF, ELISAm, r, h
3
(2)

Non-Mammalian MCM Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Mcm4 Antibody (C-12)

sc-166036mouse IgG2a κ1-300 (Saccharomyces cerevisiae)WB, IP, IF, ELISAy
3
(2)

Mcm4 Antibody (D-4)

sc-166193mouse IgG2b κ1-300 (Saccharomyces cerevisiae)WB, IP, IF, ELISAy

new

(1)

Mcm4 Antibody (D-7)

sc-166037mouse IgG2a κ1-300 (Saccharomyces cerevisiae)WB, IP, IF, ELISAy
2
(1)

MCM CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MCM2 CRISPR/Cas9 KO Plasmid (h)

sc-400959hGene KnockoutGFP0
(0)

MCM2 Double Nickase Plasmid (h)

sc-400959-NIChGene KnockoutPuromycin0
(0)

MCM2 Double Nickase Plasmid (h2)

sc-400959-NIC-2hGene KnockoutPuromycin0
(0)

MCM3 Double Nickase Plasmid (h)

sc-402076-NIChGene KnockoutPuromycin0
(0)

MCM3 Double Nickase Plasmid (h2)

sc-402076-NIC-2hGene KnockoutPuromycin0
(0)

MCM3AP CRISPR/Cas9 KO Plasmid (h)

sc-406369hGene KnockoutGFP0
(0)

MCM4 Double Nickase Plasmid (h)

sc-402451-NIChGene KnockoutPuromycin0
(0)

MCM4 Double Nickase Plasmid (h2)

sc-402451-NIC-2hGene KnockoutPuromycin0
(0)

MCM5 CRISPR/Cas9 KO Plasmid (h)

sc-401980hGene KnockoutGFP0
(0)

MCM5 Double Nickase Plasmid (h)

sc-401980-NIChGene KnockoutPuromycin0
(0)

MCM5 Double Nickase Plasmid (h2)

sc-401980-NIC-2hGene KnockoutPuromycin0
(0)

MCM6 CRISPR/Cas9 KO Plasmid (h)

sc-402146hGene KnockoutGFP0
(0)

MCM6 HDR Plasmid (h)

sc-402146-HDRhHomology Directed RepairPuromycin0
(0)

MCM6 Double Nickase Plasmid (h)

sc-402146-NIChGene KnockoutPuromycin0
(0)

MCM6 Double Nickase Plasmid (h2)

sc-402146-NIC-2hGene KnockoutPuromycin0
(0)

MCM7 CRISPR/Cas9 KO Plasmid (h)

sc-400900hGene KnockoutGFP
1
(0)

MCM7 HDR Plasmid (h)

sc-400900-HDRhHomology Directed RepairPuromycin
1
(0)

MCM7 Double Nickase Plasmid (h)

sc-400900-NIChGene KnockoutPuromycin
1
(0)

MCM7 Double Nickase Plasmid (h2)

sc-400900-NIC-2hGene KnockoutPuromycin
1
(0)

MCM8 CRISPR/Cas9 KO Plasmid (h)

sc-413655hGene KnockoutGFP0
(0)

MCM10 HDR Plasmid (h)

sc-407631-HDRhHomology Directed RepairPuromycin0
(0)

MCM CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MCM2 CRISPR Activation Plasmid (h)

sc-400959-ACThGene ActivationPuro, Blast, Hygro0
(0)

MCM2 CRISPR Activation Plasmid (m)

sc-421591-ACTmGene ActivationPuro, Blast, Hygro0
(0)

MCM2 CRISPR Activation Plasmid (m2)

sc-421591-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

MCM3 CRISPR Activation Plasmid (h)

sc-402076-ACThGene ActivationPuro, Blast, Hygro0
(0)

MCM4 CRISPR Activation Plasmid (h)

sc-402451-ACThGene ActivationPuro, Blast, Hygro0
(0)

MCM4 CRISPR Activation Plasmid (h2)

sc-402451-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MCM5 CRISPR Activation Plasmid (h)

sc-401980-ACThGene ActivationPuro, Blast, Hygro0
(0)

MCM5 CRISPR Activation Plasmid (h2)

sc-401980-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MCM6 CRISPR Activation Plasmid (h)

sc-402146-ACThGene ActivationPuro, Blast, Hygro0
(0)

MCM siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MCM2 siRNA (h)

sc-35879hGene SilencingN/A0
(0)

MCM2 shRNA Plasmid (h)

sc-35879-SHhGene SilencingPuromycin0
(0)

MCM2 shRNA (h) Lentiviral Particles

sc-35879-VhGene SilencingPuromycin0
(0)

MCM2 siRNA (m)

sc-35880mGene SilencingN/A0
(0)

MCM2 shRNA Plasmid (m)

sc-35880-SHmGene SilencingPuromycin0
(0)

MCM2 shRNA (m) Lentiviral Particles

sc-35880-VmGene SilencingPuromycin0
(0)

MCM3 siRNA (h)

sc-35881hGene SilencingN/A0
(1)

MCM3 shRNA Plasmid (h)

sc-35881-SHhGene SilencingPuromycin0
(1)

MCM3 shRNA (h) Lentiviral Particles

sc-35881-VhGene SilencingPuromycin0
(1)

MCM3 siRNA (m)

sc-35882mGene SilencingN/A0
(0)

MCM3 shRNA Plasmid (m)

sc-35882-SHmGene SilencingPuromycin0
(0)

MCM3 shRNA (m) Lentiviral Particles

sc-35882-VmGene SilencingPuromycin0
(0)

MCM3AP siRNA (h)

sc-91405hGene SilencingN/A0
(0)

MCM3AP shRNA Plasmid (h)

sc-91405-SHhGene SilencingPuromycin0
(0)

MCM3AP shRNA (h) Lentiviral Particles

sc-91405-VhGene SilencingPuromycin0
(0)

MCM3AP siRNA (m)

sc-149319mGene SilencingN/A0
(0)

MCM3AP shRNA Plasmid (m)

sc-149319-SHmGene SilencingPuromycin0
(0)

MCM3AP shRNA (m) Lentiviral Particles

sc-149319-VmGene SilencingPuromycin0
(0)

MCM4 siRNA (h)

sc-37619hGene SilencingN/A
2
(0)

MCM4 shRNA Plasmid (h)

sc-37619-SHhGene SilencingPuromycin
2
(0)

MCM4 shRNA (h) Lentiviral Particles

sc-37619-VhGene SilencingPuromycin
2
(0)

MCM4 siRNA (m)

sc-37620mGene SilencingN/A0
(0)

MCM4 shRNA Plasmid (m)

sc-37620-SHmGene SilencingPuromycin0
(0)

MCM4 shRNA (m) Lentiviral Particles

sc-37620-VmGene SilencingPuromycin0
(0)

MCM5 siRNA (h)

sc-35883hGene SilencingN/A0
(0)

MCM5 shRNA Plasmid (h)

sc-35883-SHhGene SilencingPuromycin0
(0)

MCM5 shRNA (h) Lentiviral Particles

sc-35883-VhGene SilencingPuromycin0
(0)

MCM5 siRNA (m)

sc-35884mGene SilencingN/A0
(0)

MCM5 shRNA Plasmid (m)

sc-35884-SHmGene SilencingPuromycin0
(0)

MCM5 shRNA (m) Lentiviral Particles

sc-35884-VmGene SilencingPuromycin0
(0)

MCM6 siRNA (h)

sc-35885hGene SilencingN/A0
(0)

MCM6 shRNA Plasmid (h)

sc-35885-SHhGene SilencingPuromycin0
(0)

MCM6 shRNA (h) Lentiviral Particles

sc-35885-VhGene SilencingPuromycin0
(0)

MCM6 siRNA (m)

sc-35886mGene SilencingN/A0
(0)

MCM6 shRNA Plasmid (m)

sc-35886-SHmGene SilencingPuromycin0
(0)

MCM6 shRNA (m) Lentiviral Particles

sc-35886-VmGene SilencingPuromycin0
(0)

MCM7 siRNA (h)

sc-35887hGene SilencingN/A
1
(1)

MCM7 shRNA Plasmid (h)

sc-35887-SHhGene SilencingPuromycin
1
(1)

MCM7 shRNA (h) Lentiviral Particles

sc-35887-VhGene SilencingPuromycin
1
(1)

MCM7 siRNA (m)

sc-35888mGene SilencingN/A0
(0)

MCM7 shRNA Plasmid (m)

sc-35888-SHmGene SilencingPuromycin0
(0)

MCM7 shRNA (m) Lentiviral Particles

sc-35888-VmGene SilencingPuromycin0
(0)

MCM8 siRNA (h)

sc-61002hGene SilencingN/A0
(0)

MCM8 shRNA Plasmid (h)

sc-61002-SHhGene SilencingPuromycin0
(0)

MCM8 shRNA (h) Lentiviral Particles

sc-61002-VhGene SilencingPuromycin0
(0)

MCM8 siRNA (m)

sc-61003mGene SilencingN/A0
(0)

MCM8 shRNA Plasmid (m)

sc-61003-SHmGene SilencingPuromycin0
(0)

MCM8 shRNA (m) Lentiviral Particles

sc-61003-VmGene SilencingPuromycin0
(0)

MCM9 siRNA (h)

sc-61004hGene SilencingN/A0
(0)

MCM9 shRNA Plasmid (h)

sc-61004-SHhGene SilencingPuromycin0
(0)

MCM9 shRNA (h) Lentiviral Particles

sc-61004-VhGene SilencingPuromycin0
(0)

MCM9 siRNA (m)

sc-61005mGene SilencingN/A0
(0)

MCM9 shRNA Plasmid (m)

sc-61005-SHmGene SilencingPuromycin0
(0)

MCM9 shRNA (m) Lentiviral Particles

sc-61005-VmGene SilencingPuromycin0
(0)

MCM10 siRNA (h)

sc-61000hGene SilencingN/A
1
(0)

MCM10 shRNA Plasmid (h)

sc-61000-SHhGene SilencingPuromycin
1
(0)

MCM10 shRNA (h) Lentiviral Particles

sc-61000-VhGene SilencingPuromycin
1
(0)

MCM10 siRNA (m)

sc-61001mGene SilencingN/A0
(0)

MCM10 shRNA Plasmid (m)

sc-61001-SHmGene SilencingPuromycin0
(0)

MCM10 shRNA (m) Lentiviral Particles

sc-61001-VmGene SilencingPuromycin0
(0)