EML1, an acronym for Echinoderm Microtubule-associated protein-like 1, is intimately associated with the vast network of microtubules that constitute an essential part of the cellular cytoskeleton. These microtubules are dynamic structures, constantly undergoing assembly and disassembly, shaping cellular architecture and contributing to vital processes such as mitosis. EML1, being a part of this microtubule cosmos, plays roles in governing these dynamics, ensuring microtubules function optimally and in concert with the cell's needs. The EML1 Activators represent a class of chemical compounds that, either directly or indirectly, augment the functional activity or expression of EML1, thereby influencing the dynamics of microtubules.
This group of activators is diverse in their mechanisms of action. Some EML1 Activators might interface directly with EML1, promoting its binding to microtubules or enhancing its stabilizing effects. Such direct interactions could amplify the overall impact of EML1 on the microtubule network. In contrast, other members of this class could operate more indirectly, modulating broader cellular pathways or processes that, in turn, necessitate an enhanced EML1 response. For instance, compounds that alter the general dynamics of microtubules-either promoting their assembly or hastening their disassembly-could spur the cell to utilize EML1 more intensively. The net effect would be an indirect activation of EML1 as the cell tries to counterbalance or accommodate these changes. In essence, EML1 Activators exemplify the intricate balance of cellular signaling and structural dynamics, shedding light on the delicate interplay of proteins and pathways that underlie the cell's architectural feats.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Known to stabilize microtubules, which might induce a compensatory response involving microtubule-associated proteins like EML1. | ||||||
Epothilone B, Synthetic | 152044-54-7 | sc-203944 | 2 mg | $176.00 | ||
Stabilizes microtubules, potentially influencing EML1 as a response to altered microtubule dynamics. | ||||||
Guanosine 5′-triphosphate trisodium salt | 36051-31-7 | sc-215111 sc-215111A | 10 mg 25 mg | $46.00 $71.00 | ||
Essential for tubulin polymerization; altered GTP dynamics might influence EML1 activity. | ||||||
2-Methoxyestradiol | 362-07-2 | sc-201371 sc-201371A | 10 mg 50 mg | $71.00 $288.00 | 6 | |
Impacts microtubule dynamics, potentially affecting EML1 activity indirectly. | ||||||
Purvalanol A | 212844-53-6 | sc-224244 sc-224244A | 1 mg 5 mg | $72.00 $297.00 | 4 | |
A cyclin-dependent kinase inhibitor that affects cell cycle and might indirectly influence EML1 during mitosis. | ||||||
Monastrol | 254753-54-3 | sc-202710 sc-202710A | 1 mg 5 mg | $120.00 $233.00 | 10 | |
Known to affect kinesin Eg5 and might indirectly influence microtubule-associated proteins like EML1. | ||||||
2,4-Dinitroaniline | 97-02-9 | sc-238342 | 100 g | $26.00 | ||
Affects tubulin polymerization, potentially influencing EML1's role in microtubule dynamics. | ||||||