Date published: 2026-6-4

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desmoplakin II Antibodies

Santa Cruz Biotechnology delivers a wide array of desmoplakin II monoclonal antibodies for research in cell adhesion and cytoskeletal integrity. desmoplakin II Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Desmoplakin II is a crucial component of desmosomes, which are specialized cell structures that provide mechanical strength to tissues by anchoring intermediate filaments to cell membranes. Desmoplakin II maintains the structural integrity of epithelial and cardiac tissues, making it essential for proper cellular function and tissue stability. Dysregulation of desmoplakin II has been implicated in various diseases, including cardiomyopathies and skin disorders, highlighting its importance in both health and disease. Understanding desmoplakin II function is vital for developing therapeutic strategies for related pathologies. Research utilizing desmoplakin II monoclonal antibodies can advance knowledge in cell biology and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies for desmoplakin II support researchers worldwide in advancing scientific understanding of cellular adhesion and tissue integrity.

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desmoplakin II Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

desmoplakin I/II Antibody (A-1)

sc-390975mouse IgG1 κ79-300 (h)WB, IP, IF, IHC(P), ELISAh
16
(7)

desmoplakin I/II Antibody (B-1)

sc-365981mouse IgG1 κ91-125 (h)WB, IP, IF, ELISAh
1
(1)

desmoplakin I/II Antibody (G-2)

sc-373789mouse IgG1 κ2745-2781 (h)WB, IP, IF, ELISAh

new

(1)

desmoplakin II CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

desmoplakin I/II CRISPR/Cas9 KO Plasmid (h)

sc-400818hGene KnockoutGFP0
(0)

desmoplakin I/II Double Nickase Plasmid (h)

sc-400818-NIChGene KnockoutPuromycin0
(0)

desmoplakin I/II Double Nickase Plasmid (h2)

sc-400818-NIC-2hGene KnockoutPuromycin0
(0)

desmoplakin I/II CRISPR/Cas9 KO Plasmid (m)

sc-430943mGene KnockoutGFP0
(0)

desmoplakin II CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

desmoplakin I/II CRISPR Activation Plasmid (h)

sc-400818-ACThGene ActivationPuro, Blast, Hygro0
(0)

desmoplakin II siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

desmoplakin I/II siRNA (h)

sc-43724hGene SilencingN/A0
(0)

desmoplakin I/II shRNA Plasmid (h)

sc-43724-SHhGene SilencingPuromycin0
(0)

desmoplakin I/II shRNA (h) Lentiviral Particles

sc-43724-VhGene SilencingPuromycin0
(0)

desmoplakin I/II siRNA (m)

sc-45911mGene SilencingN/A0
(0)

desmoplakin I/II shRNA Plasmid (m)

sc-45911-SHmGene SilencingPuromycin0
(0)

desmoplakin I/II shRNA (m) Lentiviral Particles

sc-45911-VmGene SilencingPuromycin0
(0)