STEP Activators
The chemical class termed STEP Activators encompasses a range of compounds that are hypothesized to indirectly influence the STEP protein and its associated signaling pathways. These compounds primarily operate by modulating various aspects of neuronal signaling and synaptic plasticity, which are key areas of STEP's involvement. Compounds like Forskolin, cAMP, and EGF can modulate signaling pathways that are potentially linked to STEP's activity in the brain. Forskolin and cAMP, known for their role in elevating intracellular cAMP levels, might influence synaptic plasticity pathways where STEP is involved. EGF, through its effect on neuronal growth and synaptic signaling, could indirectly modulate STEP activity.
Other molecules, such as Nifedipine and Lithium Chloride, affect calcium signaling and neurogenesis pathways, respectively. These pathways are crucial in neuronal function and health, and their modulation could have indirect implications for STEP activity, especially in calcium-dependent signaling processes.Additionally, compounds like Dexamethasone, Curcumin, and Sodium Butyrate, known for their effects on stress response, inflammation, and gene expression regulation, respectively, provide insight into how STEP's activity could be indirectly influenced in various neuronal contexts. Rapamycin's role in regulating neuronal growth and synaptic plasticity further highlights potential indirect pathways for influencing STEP.
Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases intracellular cAMP levels by activating adenylate cyclase, which can modulate signaling pathways involving STEP, particularly those related to synaptic plasticity and neuronal signaling. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
Activates protein kinase C (PKC), which is involved in neuronal signaling pathways. PKC activation can influence STEP activity indirectly by modulating synaptic signaling pathways. | ||||||
Adenosine 3′,5′-cyclic monophosphate | 60-92-4 | sc-217584 sc-217584A sc-217584B sc-217584C sc-217584D sc-217584E | 100 mg 250 mg 5 g 10 g 25 g 50 g | $116.00 $179.00 $265.00 $369.00 $629.00 $1150.00 | ||
As a second messenger, cAMP is involved in neuronal signaling pathways. Its elevation can indirectly influence STEP activity, particularly in pathways related to synaptic plasticity and neuronal communication. | ||||||
Nifedipine | 21829-25-4 | sc-3589 sc-3589A | 1 g 5 g | $59.00 $173.00 | 15 | |
A calcium channel blocker, altering calcium influx in neurons. Altered calcium signaling can indirectly influence STEP activity, particularly in calcium-dependent neuronal signaling pathways. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Influences several signaling pathways, including those involved in neurogenesis. Lithium can indirectly affect STEP, particularly in pathways related to neuronal health and synaptic plasticity. | ||||||
Dexamethasone | 50-02-2 | sc-29059 sc-29059B sc-29059A | 100 mg 1 g 5 g | $91.00 $139.00 $374.00 | 36 | |
A glucocorticoid that influences various signaling pathways, including those in neurons. Dexamethasone can indirectly modulate STEP activity by affecting neuronal stress response pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Affects multiple signaling pathways, including those involved in inflammation and neuroprotection. Curcumin can indirectly influence STEP by modulating neuronal signaling and stress response pathways. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Influences histone deacetylase (HDAC) activity, affecting gene expression. If STEP expression is regulated by HDAC activity, sodium butyrate could indirectly influence its activity. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
Inhibits mTOR, a key regulator in cell growth and metabolism. Rapamycin can indirectly affect STEP, particularly in pathways related to neuronal growth and synaptic plasticity. | ||||||
Serotonin hydrochloride | 153-98-0 | sc-201146 sc-201146A | 100 mg 1 g | $118.00 $187.00 | 15 | |
Stimulates serotonin receptors, which are involved in neuronal signaling. Serotonin can indirectly influence STEP activity in pathways related to mood regulation and synaptic communication. | ||||||