P504S (AMACR) Activators
P504S (AMACR) Activators refer to a class of chemical compounds or molecules that have been investigated for their potential to modulate the activity of the Alpha-methylacyl-CoA racemase (AMACR) enzyme, also known as P504S. AMACR is an enzyme that plays a significant role in the metabolism of branched-chain fatty acids and bile acid intermediates, particularly in peroxisomal and mitochondrial beta-oxidation pathways. Activators of AMACR are compounds that can enhance or stimulate the enzymatic activity of AMACR. Research in this area primarily aims to understand the regulation of AMACR function and the factors that may influence its activity.
The mechanisms by which P504S (AMACR) activators work are multifaceted and can vary depending on the specific compound or molecule in question. Some activators may directly interact with AMACR, promoting its enzymatic activity by inducing conformational changes or stabilizing its active form. Others may influence AMACR indirectly by modulating cellular conditions, such as optimizing cofactor availability or maintaining suitable pH levels. Additionally, the regulation of AMACR activity can involve post-translational modifications and interactions with other cellular proteins. Investigating P504S (AMACR) activators provides insights into the complex network of metabolic pathways where AMACR operates, shedding light on the factors that can influence its enzymatic function and its potential role in cellular lipid metabolism.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Cholic acid | 81-25-4 | sc-255020 sc-255020A sc-255020B sc-255020C sc-255020D | 25 g 100 g 500 g 1 kg 5 kg | $49.00 $123.00 $578.00 $1018.00 $4570.00 | 11 | |
Cholic acid is a primary bile acid produced in the liver. It is conjugated with glycine or taurine and released into the intestine to aid in fat digestion and absorption. Bile acids like cholic acid can be metabolized through beta-oxidation pathways, which involve AMACR. | ||||||
Chenodiol-d4 | 99102-69-9 | sc-211064 | 5 mg | $360.00 | ||
Chenodeoxycholic acid is another primary bile acid synthesized in the liver. It is also involved in fat digestion and can be metabolized through beta-oxidation pathways. | ||||||
Deoxycholic acid | 83-44-3 | sc-214865 sc-214865A sc-214865B | 5 g 25 g 1 kg | $37.00 $67.00 $941.00 | 4 | |
Deoxycholic acid is a secondary bile acid formed by the dehydroxylation of cholic acid in the intestine by gut bacteria. It can be further metabolized through pathways that may involve AMACR. | ||||||
Lithocholic acid | 434-13-9 | sc-215262 sc-215262A | 10 g 25 g | $100.00 $272.00 | 1 | |
Lithocholic acid is another secondary bile acid formed through the dehydroxylation of chenodeoxycholic acid in the intestine. Like other bile acids, it can participate in pathways related to AMACR. | ||||||
Ursodeoxycholic acid | 128-13-2 | sc-204935 sc-204935A | 1 g 5 g | $52.00 $131.00 | 4 | |
Ursodeoxycholic acid is a bile acid used therapeutically to dissolve cholesterol gallstones. While it is not a primary substrate for AMACR, it can influence bile acid metabolism and the balance of different bile acid species in the liver and intestine. | ||||||