Deoxycholic acid CAS: 83-44-3
MF: C24H40O4
MW: 392.57
A bile acid that may affect cellular signaling and gene expression.

Deoxycholic acid (CAS 83-44-3)

Deoxycholic acid | CAS 83-44-3 is rated 5.0 out of 5 by 2.
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Alternate Names: 3α,12α-Dihydroxy-5β-cholanic acid
Application: Deoxycholic acid is a bile acid that may affect cellular signaling and gene expression
CAS Number: 83-44-3
Purity: ≥98%
Molecular Weight: 392.57
Molecular Formula: C24H40O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data (including water content).

Deoxycholic acid is a bile acid that may affect cellular signaling and gene expression. It has been used to study assess how physiological concentrations of ursodeoxycholic acid (UDCA) vs. deoxycholic acid (DCA) affect barrier function in mouse intestinal tissue.

Appearance :
Powder
Physical State :
Solid
Solubility :
Soluble in water (0.24 g/l).
Storage :
Store at room temperature
Melting Point :
171-174° C (lit.)
Boiling Point :
547.15° C at 760 mmHg (Predicted)
Density :
1.13 g/cm3 (Predicted)
Refractive Index :
n20D 1.54 (Predicted)
Optical Activity :
α20/D 56°, c = 1 in EtOH
IC50 :
G-protein coupled bile acid receptor 1: EC5050 = 1.25 µM (human)
pK Values :
pKa: 4.76 (Predicted)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
3
RTECS :
FZ2100000
PubChem CID :
222528
Merck Index :
14: 2899
MDL Number :
MFCD00003673
EC Number :
201-478-5
Beilstein Registry :
3219882

Download SDS (MSDS)

Certificate of Analysis

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What is the solubility of this product?

Asked by: hawkeye11
Thanks for your question. Deoxycholic acid, sc-214865, is soluble in acetone, acetic acid, three oxygen methane, ether, ethanol. To enhance solubility please warm gently to around 35 degrees celsius and shake it in an ultrasonic bath.
Answered by: TechService7
Date published: 2020-03-07

Is this synthesized in a chemical lab or is it purified from animals?

Asked by: Raman
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Rated 5 out of 5 by from Excellent Excellent
Date published: 2016-03-20
Rated 5 out of 5 by from Abdel Abdel-Latif, MM. et al. (PubMed 26378497) found that Ursodeoxycholic acid inhibits Deoxycholic acid-induced signaling pathways in oesophageal cancer cells. -SCBT Publication Review
Date published: 2015-06-26
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