OTX2 Activators
OTX2 Activators belong to a specialized category of chemical compounds designed to modulate the activity of the Orthodenticle Homeobox 2 (OTX2) protein. OTX2 is a transcription factor and a member of the homeobox gene family that plays a critical role in embryonic development, particularly in the formation and patterning of the central nervous system, sensory organs, and forebrain structures. It is a master regulator of early neural development and is known for its ability to control the expression of a wide array of genes essential for proper brain and eye development.
OTX2 Activators are compounds engineered to interact with OTX2 and influence its transcriptional regulatory functions. These activators can either enhance or inhibit OTX2's ability to bind to specific DNA sequences and modulate target gene expression, depending on their chemical structure and mode of action. By targeting OTX2, these compounds provide researchers with a valuable tool to investigate the precise mechanisms by which OTX2 orchestrates the intricate processes of embryonic neural development and sensory organ formation. The study of OTX2 Activators is pivotal for advancing our understanding of the genetic control mechanisms underlying neurodevelopment and the establishment of sensory systems. Researchers continue to explore the precise mechanisms of OTX2 activation and its implications in various biological contexts, offering insights into the complex molecular pathways that govern early embryonic development.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid, a metabolite of Vitamin A, is known to influence embryonic development and may modulate OTX2 expression, particularly in neural and ocular tissues. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG, a major component of green tea, may exert neuroprotective effects and potentially induce OTX2 expression in neural cells, linked to its antioxidant properties. | ||||||
β-Carotene | 7235-40-7 | sc-202485 sc-202485A sc-202485B sc-202485C | 1 g 25 g 50 g 5 kg | $80.00 $351.00 $621.00 $12791.00 | 5 | |
β-Carotene, a precursor of Vitamin A, may influence OTX2 expression through its metabolization into retinoic acid, impacting embryonic development and organogenesis. | ||||||
Cholecalciferol | 67-97-0 | sc-205630 sc-205630A sc-205630B | 1 g 5 g 10 g | $71.00 $163.00 $296.00 | 2 | |
Cholecalciferol, through its active metabolites, may regulate gene expression and potentially enhance OTX2 expression, particularly in the context of neural development. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride, used in various biological studies, may impact Wnt signaling pathways and indirectly influence the expression of OTX2 in neural tissues. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin, an activator of adenylate cyclase, may play a role in neural differentiation and potentially upregulate OTX2 expression through cAMP-mediated pathways. | ||||||
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a compound found in turmeric, may have neuroprotective effects and could potentially modulate OTX2 expression, likely through its anti-inflammatory properties. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a polyphenol found in grapes, may affect gene expression and neurodevelopment, potentially influencing OTX2 expression through its antioxidant effects. | ||||||
Nicotinamide | 98-92-0 | sc-208096 sc-208096A sc-208096B sc-208096C | 100 g 250 g 1 kg 5 kg | $44.00 $66.00 $204.00 $831.00 | 6 | |
Nicotinamide, a form of Vitamin B3, may play a role in cell differentiation and survival, potentially influencing OTX2 expression in developing neural tissues. | ||||||
Sodium Butyrate | 156-54-7 | sc-202341 sc-202341B sc-202341A sc-202341C | 250 mg 5 g 25 g 500 g | $31.00 $47.00 $84.00 $222.00 | 19 | |
Sodium butyrate, a short-chain fatty acid, may influence histone modification and gene expression, potentially affecting OTX2 expression in neural cells. | ||||||