Gm13288 is a gene that encodes a protein integral to various cellular processes, especially signaling pathways. The encoded protein's precise function may depend on the cell type and the physiological context, but generally, it is involved in transmitting signals from the cell surface to the nucleus, thereby influencing cellular responses. This protein plays a critical role in cellular communication and can be involved in processes such as cell growth, differentiation, and response to external stimuli. The activation of this protein is essential for the proper functioning of these pathways and for maintaining cellular homeostasis. Activation of the protein encoded by Gm13288 is typically regulated by post-translational modifications, most notably phosphorylation. Phosphorylation is a key regulatory mechanism in cellular signaling, where the addition of a phosphate group to a protein can significantly alter its activity, usually resulting in activation. Kinases, which are enzymes that catalyze the phosphorylation of proteins, play a pivotal role in this process. The activators of Gm13288's protein, therefore, often function by initiating or enhancing the phosphorylation of proteins within the signaling pathways that include Gm13288's protein, leading to its activation.
In addition to phosphorylation, the activation of Gm13288's protein can be influenced by changes in levels of intracellular signaling molecules, such as cAMP, calcium ions, and various growth factors. These molecules can bind to specific receptors or enter cells, triggering signaling cascades that converge on the pathways involving Gm13288's protein. The activation of these pathways involves a complex network of signaling molecules and enzymes, each contributing to the precise regulation of Gm13288's protein activity. This intricate regulation is crucial for the proper response of the cell to external and internal signals. The activators of Gm13288's protein are diverse, working through different mechanisms but ultimately converging on the common goal of modulating the phosphorylation state and activity of proteins within the signaling pathways that include Gm13288's protein. This regulation ensures that Gm13288's protein is activated under appropriate conditions, playing a critical role in the cellular processes it influences.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Sodium Orthovanadate | 13721-39-6 | sc-3540 sc-3540B sc-3540A | 5 g 10 g 50 g | $49.00 $57.00 $187.00 | 142 | |
Sodium orthovanadate activates the protein encoded by Gm13288 by inhibiting protein tyrosine phosphatases, which leads to enhanced tyrosine phosphorylation. This phosphorylation can activate downstream signaling pathways involving Gm13288's protein, thereby enhancing its functional activity. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA activates the protein encoded by Gm13288 through the activation of protein kinase C (PKC). PKC phosphorylates target proteins in signaling pathways that include Gm13288's protein, leading to its activation. | ||||||
Ionomycin | 56092-82-1 | sc-3592 sc-3592A | 1 mg 5 mg | $78.00 $270.00 | 80 | |
Ionomycin activates the protein encoded by Gm13288 by increasing intracellular calcium levels, which in turn activates calcium-dependent proteins and enzymes in the signaling pathways involving Gm13288's protein, ultimately leading to its activation. | ||||||
Insulin | 11061-68-0 | sc-29062 sc-29062A sc-29062B | 100 mg 1 g 10 g | $156.00 $1248.00 $12508.00 | 82 | |
Insulin activates the protein encoded by Gm13288 by initiating a signaling cascade through its receptor. This cascade includes activation of the PI3K/Akt pathway, which is known to phosphorylate and activate several proteins, potentially including those in the pathway of Gm13288's protein, leading to its activation. | ||||||
(+)-cis,trans-Abscisic acid | 21293-29-8 | sc-202103 sc-202103A | 500 µg 1 mg | $107.00 $192.00 | ||
(+)-cis,trans-Abscisic acid activates the protein encoded by Gm13288 by binding to its receptor and initiating signaling cascades that include NF-κB and MAPK pathways. These pathways activate proteins in the Gm13288 signaling pathway, leading to its activation. | ||||||
Hydrogen Peroxide | 7722-84-1 | sc-203336 sc-203336A sc-203336B | 100 ml 500 ml 3.8 L | $31.00 $61.00 $95.00 | 28 | |
Hydrogen Peroxide activates the protein encoded by Gm13288 by acting as a signaling molecule that leads to the activation of various kinases. These kinases phosphorylate and activate proteins within the signaling pathways involving Gm13288's protein, enhancing its functional activity. | ||||||