Date published: 2026-4-24

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OTTMUSG00000005288 Activators

The Gm12063 protein, also known as Gene model 12063, plays a crucial role in cellular processes, particularly in the regulation of gene expression and signal transduction. This protein is a key player in intracellular signaling pathways, where its activation influences various downstream events. While the precise biological function of Gm12063 is still an active area of research, its involvement in cellular responses and gene regulation highlights its significance in cellular homeostasis and adaptability. Activation of Gm12063 primarily involves the modulation of intracellular signaling cascades. The activation of this protein can be triggered by various external stimuli or intracellular events that lead to specific biochemical changes within the cell. These stimuli can range from extracellular ligands binding to cell surface receptors to intracellular second messenger systems. The activation mechanisms often converge on the phosphorylation of Gm12063 or its interaction with other signaling proteins. This post-translational modification is a pivotal step in the functional activation of the protein, as it enables Gm12063 to interact with its downstream effectors, initiating a cascade of events that can ultimately lead to changes in gene expression, cell differentiation, or other cellular responses.

In conclusion, Gm12063 is a protein with a significant role in cellular signaling and gene regulation. Its activation is intricately tied to the modulation of various intracellular pathways and can be influenced by a multitude of factors. While ongoing research continues to elucidate the precise functions and mechanisms of Gm12063, its importance in cellular adaptability and response to environmental cues cannot be understated. Understanding the intricacies of Gm12063 activation contributes to our broader comprehension of cellular biology and the intricate web of signaling events that govern cell behavior and function.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Retinoic Acid, all trans

302-79-4sc-200898
sc-200898A
sc-200898B
sc-200898C
500 mg
5 g
10 g
100 g
$66.00
$325.00
$587.00
$1018.00
28
(1)

Retinoic Acid activates Gm12063 by binding to nuclear receptors, initiating gene transcription, and promoting the expression of Gm12063, thereby leading to its functional activation.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates Gm12063 by activating protein kinase C (PKC), which triggers downstream signaling pathways, resulting in phosphorylation and functional activation of the protein.

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone activates Gm12063 through glucocorticoid receptor binding, leading to changes in gene expression and ultimately promoting the functional activation of the protein.

8-Bromo-cAMP

76939-46-3sc-201564
sc-201564A
10 mg
50 mg
$126.00
$328.00
30
(1)

8-Bromo-cAMP activates Gm12063 by directly increasing intracellular cAMP levels, subsequently activating PKA, leading to phosphorylation and functional activation of the protein.

Isoproterenol Hydrochloride

51-30-9sc-202188
sc-202188A
100 mg
500 mg
$28.00
$38.00
5
(0)

Isoproterenol activates Gm12063 by binding to adrenergic receptors, which stimulate the cAMP-PKA pathway, leading to phosphorylation and functional activation of the protein.

Rolipram

61413-54-5sc-3563
sc-3563A
5 mg
50 mg
$77.00
$216.00
18
(1)

Rolipram activates Gm12063 by inhibiting phosphodiesterase (PDE), which leads to increased cAMP levels and subsequent PKA activation, resulting in the functional activation of the protein.

Dibutyryl-cAMP

16980-89-5sc-201567
sc-201567A
sc-201567B
sc-201567C
20 mg
100 mg
500 mg
10 g
$47.00
$136.00
$492.00
$4552.00
74
(7)

Dibutyryl-cAMP activates Gm12063 by elevating intracellular cAMP levels, subsequently activating PKA, leading to phosphorylation and functional activation of the protein.

Thapsigargin

67526-95-8sc-24017
sc-24017A
1 mg
5 mg
$136.00
$446.00
114
(2)

Thapsigargin activates Gm12063 by inhibiting the SERCA pump, causing calcium release from the endoplasmic reticulum, which triggers downstream signaling and functional activation of the protein.