OTTMUSG00000004461 Activators
The Triple QxxK/R motif-containing protein (Gm11818) is a pivotal player in cellular processes, and its activation is intricately linked to cyclic AMP (cAMP) signaling pathways. Although the precise function of Gm11818 is under ongoing investigation, its role in cellular physiology is becoming increasingly evident. Activation of Gm11818 is primarily mediated by the regulation of intracellular cAMP levels. Chemical activators such as forskolin, isoproterenol, IBMX, caffeine, epinephrine, rolipram, NKH477, prostaglandin E2 (PGE2), terbutaline, theophylline, and clenbuterol modulate cAMP signaling pathways. These activators either directly stimulate adenylate cyclase or inhibit phosphodiesterases, leading to an elevation in cAMP levels. The increased cAMP levels, in turn, activate Gm11818 via downstream signaling pathways.
In conclusion, Gm11818, while still having its exact function under scrutiny, is closely associated with the regulation of cAMP levels within the cell. Chemical activators play a crucial role in modulating these pathways, likely influencing the activity of Gm11818 and potentially affecting various cellular functions. Further research is necessary to elucidate the specific role of Gm11818 in cellular processes and its broader implications in physiological regulation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol activates Gm11818 through beta-adrenergic receptor stimulation, initiating adenylate cyclase activity, cAMP production, and protein activation. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX activates Gm11818 by inhibiting phosphodiesterases, resulting in elevated cAMP levels, which activate the protein via downstream signaling pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine activates Gm11818 by antagonizing adenosine receptors, leading to increased cAMP production and subsequent functional activation of the protein. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates Gm11818 by binding to beta-adrenergic receptors, initiating adenylate cyclase activity, cAMP production, and protein activation. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram activates Gm11818 by selectively inhibiting phosphodiesterase 4, increasing cAMP levels, and subsequently activating the protein. | ||||||
Cilomilast | 153259-65-5 | sc-483188 | 5 mg | $132.00 | 1 | |
NKH477 activates Gm11818 by inhibiting phosphodiesterase 3, leading to an increase in cAMP levels, which results in the functional activation of the protein. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 activates Gm11818 through its receptor EP2, triggering adenylate cyclase activity, cAMP elevation, and protein activation via downstream signaling pathways. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $32.00 $85.00 | 6 | |
Theophylline activates Gm11818 by inhibiting phosphodiesterases, increasing cAMP levels, and leading to the functional activation of the protein. | ||||||
Salbutamol | 18559-94-9 | sc-253527 sc-253527A | 25 mg 50 mg | $94.00 $141.00 | ||
Salbutamol activates Gm11818 by binding to beta-adrenergic receptors, stimulating adenylate cyclase, increasing cAMP levels, and subsequently activating the protein. | ||||||