OTTMUSG00000004012 Activators
LOC623272, also known as Gm11757, is a gene that has garnered interest due to its potential involvement in various cellular processes. While the precise function of Gm11757 is still under investigation, its activation appears to be closely linked to the regulation of cyclic AMP (cAMP) signaling pathways. Understanding the role of Gm11757 in cellular physiology is a subject of ongoing research. The activation of Gm11757 primarily involves the manipulation of intracellular cAMP levels. Chemical activators such as forskolin, isoproterenol, IBMX, caffeine, epinephrine, rolipram, NKH477, prostaglandin E2 (PGE2), terbutaline, theophylline, and clenbuterol influence cAMP signaling pathways. These activators either directly stimulate adenylate cyclase or inhibit phosphodiesterases, leading to increased cAMP production. Elevated cAMP levels subsequently activate Gm11757 via downstream signaling pathways.
In summary, while the exact function of Gm11757 is still being elucidated, its activation is closely tied to the regulation of cAMP levels within the cell. Chemical activators mentioned above modulate cAMP signaling pathways, which likely impact the activity of Gm11757 and potentially influence various cellular functions. Further research is necessary to fully comprehend the specific role of Gm11757 in cellular processes and its potential implications in physiological regulation.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol activates Gm11757 through beta-adrenergic receptor stimulation, initiating adenylate cyclase activity, cAMP production, and protein activation. | ||||||
IBMX | 28822-58-4 | sc-201188 sc-201188B sc-201188A | 200 mg 500 mg 1 g | $260.00 $350.00 $500.00 | 34 | |
IBMX activates Gm11757 by inhibiting phosphodiesterases, resulting in elevated cAMP levels, which activate the protein via downstream signaling pathways. | ||||||
Caffeine | 58-08-2 | sc-202514 sc-202514A sc-202514B sc-202514C sc-202514D | 50 g 100 g 250 g 1 kg 5 kg | $33.00 $67.00 $97.00 $192.00 $775.00 | 13 | |
Caffeine activates Gm11757 by antagonizing adenosine receptors, leading to increased cAMP production and subsequent functional activation of the protein. | ||||||
(−)-Epinephrine | 51-43-4 | sc-205674 sc-205674A sc-205674B sc-205674C sc-205674D | 1 g 5 g 10 g 100 g 1 kg | $41.00 $104.00 $201.00 $1774.00 $16500.00 | ||
Epinephrine activates Gm11757 by binding to beta-adrenergic receptors, initiating adenylate cyclase activity, cAMP production, and protein activation. | ||||||
Rolipram | 61413-54-5 | sc-3563 sc-3563A | 5 mg 50 mg | $77.00 $216.00 | 18 | |
Rolipram activates Gm11757 by selectively inhibiting phosphodiesterase 4, increasing cAMP levels, and subsequently activating the protein. | ||||||
Cilomilast | 153259-65-5 | sc-483188 | 5 mg | $132.00 | 1 | |
NKH477 activates Gm11757 by inhibiting phosphodiesterase 3, leading to an increase in cAMP levels, which results in the functional activation of the protein. | ||||||
PGE2 | 363-24-6 | sc-201225 sc-201225C sc-201225A sc-201225B | 1 mg 5 mg 10 mg 50 mg | $57.00 $159.00 $275.00 $678.00 | 37 | |
PGE2 activates Gm11757 through its receptor EP2, triggering adenylate cyclase activity, cAMP elevation, and protein activation via downstream signaling pathways. | ||||||
Theophylline | 58-55-9 | sc-202835 sc-202835A sc-202835B | 5 g 25 g 100 g | $20.00 $32.00 $85.00 | 6 | |
Theophylline activates Gm11757 by inhibiting phosphodiesterases, increasing cAMP levels, and leading to the functional activation of the protein. | ||||||
Salbutamol | 18559-94-9 | sc-253527 sc-253527A | 25 mg 50 mg | $94.00 $141.00 | ||
Albuterol activates Gm11757 by binding to beta-adrenergic receptors, stimulating adenylate cyclase, increasing cAMP levels, and subsequently activating the protein. | ||||||