Na+ CP type IIIβ Activators
Na+ CP type IIIβ" likely refers to a subtype of the Type III sodium-dependent phosphate cotransporters (NaPi-III), specifically the β isoform. These transporters are integral membrane proteins involved in the regulation of phosphate homeostasis in the body by mediating the cotransport of sodium (Na+) and phosphate (Pi) ions across cell membranes.The Type III sodium-dependent phosphate cotransporters are part of a larger family of solute carrier transporters (SLC), particularly the SLC34 family. They play a crucial role in phosphate balance, which is vital for various physiological processes including bone formation, energy metabolism, and cell signaling.
The Type III transporters are characterized by their ability to transport phosphate ions into cells in a sodium-dependent manner, meaning the transport of phosphate is coupled with the transport of sodium ions. This coupling is essential for the efficient uptake of phosphate, especially in environments where phosphate concentration is low.The β isoform (IIIβ) of these transporters has specific characteristics and tissue distribution. It may differ from other isoforms in aspects such as regulation, affinity for phosphate, and response to various physiological and hormonal influences. These differences allow for a finely tuned regulation of phosphate homeostasis in different tissues and under various physiological conditions.
SEE ALSO...
Items 1 to 10 of 12 total
Display:
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Ouabain-d3 (Major) | sc-478417 | 1 mg | $516.00 | |||
Ouabain is a known inhibitor of the Na+/K+-ATPase pump, and its action can lead to increased intracellular sodium levels, potentially influencing the activity of sodium-dependent cotransporters. | ||||||
12β-Hydroxydigitoxin | 20830-75-5 | sc-213604 sc-213604A | 1 g 5 g | $143.00 $694.00 | ||
12β-Hydroxydigitoxin, another Na+/K+-ATPase inhibitor, similarly may affect sodium homeostasis, indirectly impacting Na+ CP type IIIβ activity. | ||||||
Amiloride • HCl | 2016-88-8 | sc-3578 sc-3578A | 25 mg 100 mg | $22.00 $57.00 | 6 | |
Amiloride is a diuretic that acts as a sodium channel blocker, potentially altering sodium balance and indirectly affecting sodium cotransporters. | ||||||
Furosemide | 54-31-9 | sc-203961 | 50 mg | $41.00 | ||
Furosemide, a loop diuretic, inhibits the Na+/K+/2Cl- cotransporter in the kidney, which could have secondary effects on other sodium transporters. | ||||||
Hydrochlorothiazide | 58-93-5 | sc-207738 sc-207738A sc-207738B sc-207738C sc-207738D | 5 g 25 g 50 g 100 g 250 g | $55.00 $240.00 $333.00 $562.00 $988.00 | ||
Hydrochlorothiazide, a thiazide diuretic, affects sodium reabsorption in the distal convoluted tubule, potentially influencing Na+ CP type IIIβ. | ||||||
Captopril | 62571-86-2 | sc-200566 sc-200566A | 1 g 5 g | $49.00 $91.00 | 21 | |
Captopril, an ACE inhibitor, affects the renin-angiotensin system, which regulates sodium balance and could impact sodium cotransporters. | ||||||
Losartan | 114798-26-4 | sc-353662 | 100 mg | $130.00 | 18 | |
Losartan, an angiotensin II receptor blocker, also affects the renin-angiotensin system and sodium homeostasis. | ||||||
Spironolactone | 52-01-7 | sc-204294 | 50 mg | $109.00 | 3 | |
Spironolactone, a potassium-sparing diuretic, antagonizes aldosterone and could indirectly influence sodium transport mechanisms. | ||||||
Verapamil | 52-53-9 | sc-507373 | 1 g | $374.00 | ||
Verapamil, a calcium channel blocker, indirectly affects sodium channels and transporters by altering cellular ion balance. | ||||||
Amlodipine | 88150-42-9 | sc-200195 sc-200195A | 100 mg 1 g | $74.00 $166.00 | 2 | |
Amlodipine, another calcium channel blocker, may have indirect effects on sodium transport processes. | ||||||