C11orf10_1810006K21Rik Activators
C11orf10/1810006K21Rik Activators encompass a diverse array of chemical compounds that serve to indirectly enhance the activity of C11orf10/1810006K21Rik through distinct signaling mechanisms. This enhancement is initiated by molecules such as Forskolin and Isoproterenol, which increase intracellular cAMP levels, subsequently activating PKA that can phosphorylate C11orf10/1810006K21Rik, thereby augmenting its activity. Similarly, the cAMP analog 8-Bromo-cAMP bypasses upstream adenylyl cyclase activation to directly activate PKA, leading to enhanced C11orf10/1810006K21Rik function. On another front, PMA activates PKC, which sets off a phosphorylation cascade likely to impinge upon C11orf10/1810006K21Rik, modifying its interactions and enhancing its activity, while Ionomycin elevates intracellular calcium, activating calcium-dependent kinases that may directly or indirectly phosphorylate and activate C11orf10/1810006K21Rik.
Continuing the theme of indirect activation, Genistein and EGCG, by inhibiting tyrosine and other kinases, respectively, may reduce inhibitory phosphorylation or competition, allowing for enhanced activation of C11orf10/1810006K21Rik by facilitating kinase access.
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Items 1 to 10 of 11 total
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Isoproterenol Hydrochloride | 51-30-9 | sc-202188 sc-202188A | 100 mg 500 mg | $28.00 $38.00 | 5 | |
Isoproterenol is a non-selective beta-adrenergic agonist that induces the activation of adenylyl cyclase via the beta-adrenoceptor, resulting in increased cAMP levels. This, in turn, activates PKA, which potentially phosphorylates and enhances the activity of C11orf10/1810006K21Rik. | ||||||
PMA | 16561-29-8 | sc-3576 sc-3576A sc-3576B sc-3576C sc-3576D | 1 mg 5 mg 10 mg 25 mg 100 mg | $41.00 $132.00 $214.00 $500.00 $948.00 | 119 | |
PMA is a potent activator of protein kinase C (PKC). Activated PKC can phosphorylate C11orf10/1810006K21Rik or downstream targets that may lead to its enhanced functional activity. | ||||||
Ionomycin, free acid | 56092-81-0 | sc-263405 sc-263405A | 1 mg 5 mg | $96.00 $264.00 | 2 | |
Ionomycin is a calcium ionophore that increases intracellular calcium levels. Elevated calcium can activate calcium-dependent protein kinases such as calmodulin-dependent kinase (CaMK), which could phosphorylate and activate C11orf10/1810006K21Rik. | ||||||
8-Bromo-cAMP | 76939-46-3 | sc-201564 sc-201564A | 10 mg 50 mg | $126.00 $328.00 | 30 | |
8-Bromo-cAMP is a cell-permeable cAMP analog that activates PKA. Activated PKA can enhance the activity of C11orf10/1810006K21Rik by phosphorylation. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein is a tyrosine kinase inhibitor that can lead to reduced competition for phosphorylation sites on proteins, potentially increasing the phosphorylation and activity of C11orf10/1810006K21Rik by other kinases. | ||||||
(−)-Epigallocatechin Gallate | 989-51-5 | sc-200802 sc-200802A sc-200802B sc-200802C sc-200802D sc-200802E | 10 mg 50 mg 100 mg 500 mg 1 g 10 g | $43.00 $73.00 $126.00 $243.00 $530.00 $1259.00 | 11 | |
EGCG is a kinase inhibitor that may lead to an increase in the activity of C11orf10/1810006K21Rik by reducing the inhibitory phosphorylation of proteins that interact with or regulate C11orf10/1810006K21Rik. | ||||||
U-0126 | 109511-58-2 | sc-222395 sc-222395A | 1 mg 5 mg | $64.00 $246.00 | 136 | |
U0126 is an inhibitor of MEK1/2, which are part of the MAPK/ERK pathway. By inhibiting this pathway, U0126 may lead to compensatory activation of alternative pathways that enhance the activity of C11orf10/1810006K21Rik. | ||||||
LY 294002 | 154447-36-6 | sc-201426 sc-201426A | 5 mg 25 mg | $123.00 $400.00 | 148 | |
LY294002 is a PI3K inhibitor that could lead to changes in downstream signaling pathways, potentially resulting in the activation of alternative pathways that enhance the activity of C11orf10/1810006K21Rik. | ||||||
D-erythro-Sphingosine-1-phosphate | 26993-30-6 | sc-201383 sc-201383D sc-201383A sc-201383B sc-201383C | 1 mg 2 mg 5 mg 10 mg 25 mg | $165.00 $322.00 $570.00 $907.00 $1727.00 | 7 | |
Sphingosine-1-phosphate is a bioactive lipid that acts on sphingosine-1-phosphate receptors, leading to downstream signaling events that may enhance the activity of C11orf10/1810006K21Rik by modulating its interaction with other signaling molecules. | ||||||
Thapsigargin | 67526-95-8 | sc-24017 sc-24017A | 1 mg 5 mg | $136.00 $446.00 | 114 | |
Thapsigargin is a SERCA pump inhibitor that raises intracellular calcium levels, potentially activating calcium-dependent signaling pathways and thereby enhancing the activity of C11orf10/1810006K21Rik. | ||||||