Date published: 2026-7-12

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TCF Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of TCF Antibodies for investigating T-cell factor proteins in various biological processes. TCF Antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA).TCF proteins function as transcription factors within the Wnt signaling pathway, driving cell proliferation, differentiation, and development. TCF proteins regulate gene expression in response to Wnt signals, influencing crucial processes such as embryogenesis and tissue homeostasis. Abnormal TCF protein activity has been linked to various diseases, including cancer, highlighting their significance as therapeutic targets.Monoclonal TCF antibodies enable researchers to explore molecular mechanisms, cellular pathways, and disease progression. Scientists can investigate protein-protein interactions, subcellular localization patterns, and expression levels in different tissue types. Advanced research applications include studying developmental biology, cancer research, and stem cell biology. TCF monoclonal antibodies from Santa Cruz Biotechnology support cutting-edge research that advances scientific understanding of cellular signaling and disease mechanisms.

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TCF Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

TCF-1 Antibody (C-5)

sc-271453mouse IgG2a κ1-118 (h)WB, IP, IF, IHC(P), ELISAm, r, h
10
(6)

TCF-3 Antibody (E-2)

sc-166411mouse IgG1 κ97-126 (m)WB, IP, IF, ELISAm, r, h
6
(6)

TCF-3 Antibody (F-5)

sc-398640mouse IgG1 κ421-575 (m)WB, IP, IF, ELISAm, r, h

new

(1)

TCF7L2/TCF4 Antibody (D-4)

sc-166699mouse IgG1 κ565-592 (h)WB, IP, IF, ELISAm, r, h
52
(23)

TCF7L2/TCF4 Antibody (F-7)

sc-271288mouse IgG3 κ565-592 (h)WB, IP, IF, ELISAm, r, h
1
(3)

TCF7L2/TCF4 Antibody (H-7)

sc-271287mouse IgG3 κ565-592 (h)WB, IP, IF, ELISAm, r, h
4
(3)

TCF-19 Antibody (H-2)

sc-390923mouse IgG2a κ14-160 (h)WB, IP, IF, ELISAm, r, h

new

(1)

TCF-19 Antibody (F-27)

sc-101169mouse IgG1 κ17-103 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(2)

TCF siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

TCF-1 siRNA (h)

sc-106926hGene SilencingN/A
1
(0)

TCF-1 shRNA Plasmid (h)

sc-106926-SHhGene SilencingPuromycin
1
(0)

TCF-1 shRNA (h) Lentiviral Particles

sc-106926-VhGene SilencingPuromycin
1
(0)

TCF-1 siRNA (m)

sc-36617mGene SilencingN/A
1
(0)

TCF-1 shRNA Plasmid (m)

sc-36617-SHmGene SilencingPuromycin
1
(0)

TCF-1 shRNA (m) Lentiviral Particles

sc-36617-VmGene SilencingPuromycin
1
(0)

TCF-3 siRNA (h)

sc-36618hGene SilencingN/A
3
(0)

TCF-3 shRNA Plasmid (h)

sc-36618-SHhGene SilencingPuromycin
3
(0)

TCF-3 shRNA (h) Lentiviral Particles

sc-36618-VhGene SilencingPuromycin
3
(0)

TCF-3 siRNA (m)

sc-36619mGene SilencingN/A0
(0)

TCF-3 shRNA Plasmid (m)

sc-36619-SHmGene SilencingPuromycin0
(0)

TCF-3 shRNA (m) Lentiviral Particles

sc-36619-VmGene SilencingPuromycin0
(0)

TCF7L2/TCF4 siRNA (h)

sc-43525hGene SilencingN/A
14
(0)

TCF7L2/TCF4 shRNA Plasmid (h)

sc-43525-SHhGene SilencingPuromycin
14
(0)

TCF7L2/TCF4 shRNA (h) Lentiviral Particles

sc-43525-VhGene SilencingPuromycin
14
(0)

TCF7L2/TCF4 siRNA (m)

sc-43526mGene SilencingN/A
4
(0)

TCF7L2/TCF4 shRNA Plasmid (m)

sc-43526-SHmGene SilencingPuromycin
4
(0)

TCF7L2/TCF4 shRNA (m) Lentiviral Particles

sc-43526-VmGene SilencingPuromycin
4
(0)

TCF-19 siRNA (h)

sc-63113hGene SilencingN/A
2
(0)

TCF-19 shRNA Plasmid (h)

sc-63113-SHhGene SilencingPuromycin
2
(0)

TCF-19 shRNA (h) Lentiviral Particles

sc-63113-VhGene SilencingPuromycin
2
(0)

TCF-19 siRNA (m)

sc-63114mGene SilencingN/A0
(0)

TCF-19 shRNA Plasmid (m)

sc-63114-SHmGene SilencingPuromycin0
(0)

TCF-19 shRNA (m) Lentiviral Particles

sc-63114-VmGene SilencingPuromycin0
(0)

TCF23 siRNA (h)

sc-94492hGene SilencingN/A0
(0)

TCF23 shRNA Plasmid (h)

sc-94492-SHhGene SilencingPuromycin0
(0)

TCF23 shRNA (h) Lentiviral Particles

sc-94492-VhGene SilencingPuromycin0
(0)

TCF23 siRNA (m)

sc-154136mGene SilencingN/A0
(0)

TCF23 shRNA Plasmid (m)

sc-154136-SHmGene SilencingPuromycin0
(0)

TCF23 shRNA (m) Lentiviral Particles

sc-154136-VmGene SilencingPuromycin0
(0)

TCF CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TCF-1 CRISPR/Cas9 KO Plasmid (h)

sc-401584Gene Knockouth0
(0)

TCF-1 CRISPR/Cas9 KO Plasmid (m)

sc-423299Gene Knockoutm0
(0)

TCF-1 HDR Plasmid (m)

sc-423299-HDRHomology Directed Repairm0
(0)

TCF-3 CRISPR/Cas9 KO Plasmid (h)

sc-400821Gene Knockouth0
(0)

TCF7L2/TCF4 CRISPR/Cas9 KO Plasmid (h2)

sc-400607-KO-2Gene Knockouth0
(0)

TCF7L2/TCF4 HDR Plasmid (h2)

sc-400607-HDR-2Homology Directed Repairh0
(0)

TCF7L2/TCF4 CRISPR/Cas9 KO Plasmid (m2)

sc-423301-KO-2Gene Knockoutm0
(0)

TCF7L2/TCF4 HDR Plasmid (m2)

sc-423301-HDR-2Homology Directed Repairm0
(0)

TCF-19 CRISPR/Cas9 KO Plasmid (h)

sc-404549Gene Knockouth0
(0)

TCF CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TCF-1 Double Nickase Plasmid (m)

sc-423299-NICGene Knockoutm0
(0)

TCF-1 Double Nickase Plasmid (m2)

sc-423299-NIC-2Gene Knockoutm0
(0)

TCF-3 Double Nickase Plasmid (h)

sc-400821-NICGene Knockouth0
(0)

TCF-3 Double Nickase Plasmid (h2)

sc-400821-NIC-2Gene Knockouth0
(0)

TCF7L2/TCF4 Double Nickase Plasmid (h)

sc-400607-NICGene Knockouth0
(0)

TCF7L2/TCF4 Double Nickase Plasmid (h2)

sc-400607-NIC-2Gene Knockouth0
(0)

TCF CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

TCF-1 CRISPR Activation Plasmid (m)

sc-423299-ACTGene Activationm0
(0)

TCF-3 CRISPR Activation Plasmid (h)

sc-400821-ACTGene Activationh0
(0)

TCF7L2/TCF4 CRISPR Activation Plasmid (h)

sc-400607-ACTGene Activationh0
(0)

TCF7L2/TCF4 CRISPR Activation Plasmid (h2)

sc-400607-ACT-2Gene Activationh0
(0)

TCF7L2/TCF4 Lentiviral Activation Particles (h)

sc-400607-LACGene Activationh0
(0)

TCF-19 CRISPR Activation Plasmid (h)

sc-404549-ACTGene Activationh0
(0)