Date published: 2026-7-24

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α-actinin Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of α-actinin Antibodies for research focused on understanding cellular organization and function. Monoclonal α-actinin Antibodies are compatible with multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). α-actinin is a crucial actin-binding protein that plays a significant role in the organization of the cytoskeleton and the maintenance of cell shape. In muscle cells, α-actinin facilitates contraction and maintains structural integrity, while in non-muscle cells, α-actinin contributes to cell adhesion and motility. Understanding α-actinin function is vital for elucidating mechanisms underlying various cellular processes and diseases. Researchers can utilize α-actinin monoclonal antibodies to investigate cytoskeletal dynamics, muscle function, and cell migration. Advanced visualization techniques with α-actinin monoclonal antibodies enable detailed analysis of protein localization and interactions. Multiple conjugation options are available, including horseradish peroxidase (HRP), phycoerythrin (PE), and fluorescein isothiocyanate (FITC), allowing for versatile experimental approaches. Santa Cruz Biotechnology monoclonal antibodies for α-actinin research continue to advance scientific understanding of cellular architecture and disease mechanisms.

SEE ALSO...

α-actinin Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

α-actinin Antibody (H-2)

sc-17829mouse IgG1 κ593-892 (h)WB, IP, IF, IHC(P), ELISAm, r, h
194
(31)

α-actinin Antibody (B-12)

sc-166524mouse IgG2a κC-terminal (h)WB, IP, IF, IHC(P), ELISAm, r, h
24
(6)

α-actinin-4 Antibody (G-4)

sc-390205mouse IgG2a κ610-660 (h)WB, IP, IF, IHC(P), ELISAm, r, h
16
(9)

α-actinin-4 Antibody (LW-M23)

sc-134236mouse IgG2a κ592-702 (h)WB, IP, IF, IHC(P), ELISAm, r, h
9
(5)

α-actinin-4 Antibody (A-8)

sc-393495mouse IgG1 κ1-22 (h)WB, IP, IF, IHC(P), ELISAm, r, h
12
(4)

α-actinin-4 Antibody (B-11)

sc-390180mouse IgG2a κ610-660 (h)WB, IP, IF, IHC(P), ELISAm, r, h
1
(3)

α-actinin-4 Antibody (D-3)

sc-398088mouse IgM κ495-522 (h)WB, IP, IF, ELISAm, r, h

new

(3)

α-actinin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

α-actinin-1 siRNA (h)

sc-43095hGene SilencingN/A
1
(0)

α-actinin-1 shRNA Plasmid (h)

sc-43095-SHhGene SilencingPuromycin
1
(0)

α-actinin-1 shRNA (h) Lentiviral Particles

sc-43095-VhGene SilencingPuromycin
1
(0)

α-actinin-1 siRNA (m)

sc-43096mGene SilencingN/A
1
(0)

α-actinin-1 shRNA Plasmid (m)

sc-43096-SHmGene SilencingPuromycin
1
(0)

α-actinin-1 shRNA (m) Lentiviral Particles

sc-43096-VmGene SilencingPuromycin
1
(0)

α-actinin-2 siRNA (h)

sc-43097hGene SilencingN/A0
(0)

α-actinin-2 shRNA Plasmid (h)

sc-43097-SHhGene SilencingPuromycin0
(0)

α-actinin-2 shRNA (h) Lentiviral Particles

sc-43097-VhGene SilencingPuromycin0
(0)

α-actinin-2 siRNA (m)

sc-43098mGene SilencingN/A0
(0)

α-actinin-2 shRNA Plasmid (m)

sc-43098-SHmGene SilencingPuromycin0
(0)

α-actinin-2 shRNA (m) Lentiviral Particles

sc-43098-VmGene SilencingPuromycin0
(0)

α-actinin-3 siRNA (h)

sc-43099hGene SilencingN/A0
(0)

α-actinin-3 shRNA Plasmid (h)

sc-43099-SHhGene SilencingPuromycin0
(0)

α-actinin-3 shRNA (h) Lentiviral Particles

sc-43099-VhGene SilencingPuromycin0
(0)

α-actinin-3 siRNA (m)

sc-43100mGene SilencingN/A0
(0)

α-actinin-3 shRNA Plasmid (m)

sc-43100-SHmGene SilencingPuromycin0
(0)

α-actinin-3 shRNA (m) Lentiviral Particles

sc-43100-VmGene SilencingPuromycin0
(0)

α-actinin-4 siRNA (h)

sc-43101hGene SilencingN/A
4
(0)

α-actinin-4 shRNA Plasmid (h)

sc-43101-SHhGene SilencingPuromycin
4
(0)

α-actinin-4 shRNA (h) Lentiviral Particles

sc-43101-VhGene SilencingPuromycin
4
(0)

α-actinin-4 siRNA (m)

sc-43102mGene SilencingN/A
2
(0)

α-actinin-4 shRNA Plasmid (m)

sc-43102-SHmGene SilencingPuromycin
2
(0)

α-actinin-4 shRNA (m) Lentiviral Particles

sc-43102-VmGene SilencingPuromycin
2
(0)

α-actinin CRISPR Knockout (KO) and HDR Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

α-actinin-1 CRISPR/Cas9 KO Plasmid (h)

sc-400379Gene Knockouth0
(0)

α-actinin-1 HDR Plasmid (h)

sc-400379-HDRHomology Directed Repairh0
(0)

α-actinin-1 CRISPR/Cas9 KO Plasmid (m2)

sc-430958-KO-2Gene Knockoutm0
(0)

α-actinin-2 CRISPR/Cas9 KO Plasmid (h)

sc-401186Gene Knockouth0
(0)

α-actinin-2 CRISPR/Cas9 KO Plasmid (m2)

sc-418971-KO-2Gene Knockoutm0
(0)

α-actinin-3 CRISPR/Cas9 KO Plasmid (m)

sc-418972Gene Knockoutm0
(0)

α-actinin-4 CRISPR/Cas9 KO Plasmid (h2)

sc-400548-KO-2Gene Knockouth0
(0)

α-actinin CRISPR Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

α-actinin-1 Double Nickase Plasmid (h)

sc-400379-NICGene Knockouth0
(0)

α-actinin-1 Double Nickase Plasmid (h2)

sc-400379-NIC-2Gene Knockouth0
(0)

α-actinin-2 Double Nickase Plasmid (h)

sc-401186-NICGene Knockouth0
(0)

α-actinin-2 Double Nickase Plasmid (h2)

sc-401186-NIC-2Gene Knockouth0
(0)

α-actinin-3 Double Nickase Plasmid (h)

sc-401486-NICGene Knockouth0
(0)

α-actinin-3 Double Nickase Plasmid (h2)

sc-401486-NIC-2Gene Knockouth0
(0)

α-actinin-4 Double Nickase Plasmid (h)

sc-400548-NICGene Knockouth0
(0)

α-actinin-4 Double Nickase Plasmid (h2)

sc-400548-NIC-2Gene Knockouth0
(0)

α-actinin CRISPR Activation Plasmids and Lentiviral Particles

Empty Table HeaderProduct NameCATALOG #APPLICATIONSSpeciesCitationsRATING

α-actinin-1 CRISPR Activation Plasmid (h)

sc-400379-ACTGene Activationh0
(0)

α-actinin-1 CRISPR Activation Plasmid (m)

sc-430958-ACTGene Activationm0
(0)

α-actinin-1 Lentiviral Activation Particles (m)

sc-430958-LACGene Activationm0
(0)

α-actinin-2 CRISPR Activation Plasmid (h)

sc-401186-ACTGene Activationh0
(0)

α-actinin-4 CRISPR Activation Plasmid (h)

sc-400548-ACTGene Activationh0
(0)

α-actinin-4 CRISPR Activation Plasmid (h2)

sc-400548-ACT-2Gene Activationh0
(0)