Date published: 2026-4-25

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MEK-1 Antibodies

Santa Cruz Biotechnology features a diverse variety of MEK-1 monoclonal antibodies for research in understanding MEK-1 protein's role in cellular signaling pathways. MEK-1 monoclonal antibodies are suitable for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). MEK-1, also known as MAPK/ERK kinase 1, is a key component of the MAPK signaling cascade, which regulates essential cellular processes such as proliferation, differentiation, and survival. MEK-1's dysregulation is often implicated in various cancers and other diseases, making it a significant target for therapeutic intervention. Understanding the function and regulation of MEK-1 is crucial for advancing research in cancer biology and developing targeted treatments. Researchers worldwide rely on MEK-1 monoclonal antibodies to investigate cellular signaling mechanisms and their impact on disease progression. MEK-1 monoclonal antibodies enable detailed analysis of protein expression patterns and interactions in various experimental settings. Santa Cruz Biotechnology monoclonal antibodies for MEK-1 continue to support breakthrough discoveries in cancer research and therapeutic development.

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MEK-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

MEK-1 Antibody (H-8)

sc-6250mouse IgG2b κFL (h)WB, IP, IF, IHC(P), ELISAm, r, h
94
(33)

MEK-1 Antibody (A-8)

sc-365800mouse IgG2a κC-Terminal (r)WB, IP, IF, IHC(P), ELISAm, r, h
1
(4)

MEK-1/2 Antibody (9G3)

sc-81504mouse IgG2a(h)WB, IPm, r, h and canine
51
(8)

Phospho-Specific MEK-1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

p-MEK-1 Antibody (B-4)

sc-271914mouse IgG1 κSer 298 (h)WB, IP, IF, ELISAm, r, h
13
(9)

p-MEK-1 Antibody (47.Ser 222)

sc-136542mouse IgASer 222 (h)WB, IP, ELISAm, r, h
4
(5)

p-MEK-1/2 Antibody (7E10)

sc-81503mouse IgG1Ser 218/222 (h)WB, IPm, r, h and canine
44
(5)

MEK-1 CRISPR Knockout, HDR and Double Nickase Plasmids

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MEK-1 CRISPR/Cas9 KO Plasmid (h2)

sc-400397-KO-2hGene KnockoutGFP0
(0)

MEK-1 HDR Plasmid (h2)

sc-400397-HDR-2hHomology Directed RepairPuromycin0
(0)

MEK-1 Double Nickase Plasmid (h)

sc-400397-NIChGene KnockoutPuromycin0
(0)

MEK-1 Double Nickase Plasmid (h2)

sc-400397-NIC-2hGene KnockoutPuromycin0
(0)

MEK-1 CRISPR/Cas9 KO Plasmid (m)

sc-424031mGene KnockoutGFP0
(0)

MEK-1 HDR Plasmid (m)

sc-424031-HDRmHomology Directed RepairPuromycin0
(0)

MEK-1 Double Nickase Plasmid (m)

sc-424031-NICmGene KnockoutPuromycin0
(0)

MEK-1 Double Nickase Plasmid (m2)

sc-424031-NIC-2mGene KnockoutPuromycin0
(0)

MEK-1 CRISPR Activation Products

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MEK-1 CRISPR Activation Plasmid (h)

sc-400397-ACThGene ActivationPuro, Blast, Hygro0
(0)

MEK-1 CRISPR Activation Plasmid (h2)

sc-400397-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

MEK-1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

MEK-1 siRNA (h)

sc-29396hGene SilencingN/A
19
(0)

MEK-1 shRNA Plasmid (h)

sc-29396-SHhGene SilencingPuromycin
19
(0)

MEK-1 shRNA (h) Lentiviral Particles

sc-29396-VhGene SilencingPuromycin
19
(0)

MEK-1 siRNA (m)

sc-35904mGene SilencingN/A
5
(0)

MEK-1 shRNA Plasmid (m)

sc-35904-SHmGene SilencingPuromycin
5
(0)

MEK-1 shRNA (m) Lentiviral Particles

sc-35904-VmGene SilencingPuromycin
5
(0)