Date published: 2026-5-6

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HP1 Antibodies

Santa Cruz Biotechnology supplies a comprehensive collection of HP1 Antibodies for advanced research in the field of epigenetics. HP1 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HP1 proteins regulate gene expression and chromatin structure, contributing to processes such as transcriptional silencing and heterochromatin formation. Understanding HP1 protein function is essential for investigating various biological mechanisms and disease states, including cancer and developmental disorders. Researchers can examine HP1 protein distribution patterns across different cell types and tissues to better understand their role in normal development and disease progression. Advanced imaging techniques combined with HP1 monoclonal antibodies enable detailed visualization of protein localization and interactions within cellular compartments. Studying HP1 proteins provides insights into fundamental cellular processes and potential therapeutic targets. Santa Cruz Biotechnology monoclonal antibodies for HP1 proteins support researchers worldwide in advancing scientific understanding of epigenetic regulation and its impact on human health.

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HP1 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HP1 Antibody (E-6)

sc-515341mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h
9
(6)

HP1α Antibody (GA-62)

sc-130446mouse IgG1 κFL (h)WB, IP, IF, ELISAm, r, h
5
(9)

HP1β Antibody (4D7B8)

sc-517288mouse IgG1 κFL (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
3
(2)

HP1β Antibody (MAC353)

sc-56704rat IgG2bC-Terminal (m)WB, IP, IFm, r, h

new

(4)

HP1γ Antibody (F-1)

sc-398562mouse IgG2a κ1-104 (h)WB, IP, IF, IHC(P), ELISAm, r, h
8
(9)

HP1γ Antibody (E-7)

sc-365085mouse IgG2b κ6-25 (h)WB, IP, IF, ELISAm, r, h
3
(2)

HP1 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HP1β CRISPR/Cas9 KO Plasmid (h)

sc-403235hGene KnockoutGFP0
(0)

HP1γ Double Nickase Plasmid (h)

sc-417205-NIChGene KnockoutPuromycin0
(0)

HP1γ Double Nickase Plasmid (h2)

sc-417205-NIC-2hGene KnockoutPuromycin0
(0)

HP1 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HP1γ CRISPR Activation Plasmid (h)

sc-417205-ACThGene ActivationPuro, Blast, Hygro0
(0)

HP1γ CRISPR Activation Plasmid (h2)

sc-417205-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HP1γ Lentiviral Activation Particles (h)

sc-417205-LAChGene ActivationPuro, Blast, Hygro0
(0)

HP1 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HP1α siRNA (h)

sc-37737hGene SilencingN/A
1
(0)

HP1α shRNA Plasmid (h)

sc-37737-SHhGene SilencingPuromycin
1
(0)

HP1α shRNA (h) Lentiviral Particles

sc-37737-VhGene SilencingPuromycin
1
(0)

HP1α siRNA (m)

sc-37738mGene SilencingN/A
1
(0)

HP1α shRNA Plasmid (m)

sc-37738-SHmGene SilencingPuromycin
1
(0)

HP1α shRNA (m) Lentiviral Particles

sc-37738-VmGene SilencingPuromycin
1
(0)

HP1β siRNA (h)

sc-35587hGene SilencingN/A0
(0)

HP1β shRNA Plasmid (h)

sc-35587-SHhGene SilencingPuromycin0
(0)

HP1β shRNA (h) Lentiviral Particles

sc-35587-VhGene SilencingPuromycin0
(0)

HP1β siRNA (m)

sc-35588mGene SilencingN/A
2
(0)

HP1β shRNA Plasmid (m)

sc-35588-SHmGene SilencingPuromycin
2
(0)

HP1β shRNA (m) Lentiviral Particles

sc-35588-VmGene SilencingPuromycin
2
(0)

HP1γ siRNA (h)

sc-35589hGene SilencingN/A
4
(0)

HP1γ shRNA Plasmid (h)

sc-35589-SHhGene SilencingPuromycin
4
(0)

HP1γ shRNA (h) Lentiviral Particles

sc-35589-VhGene SilencingPuromycin
4
(0)

HP1γ siRNA (m)

sc-35590mGene SilencingN/A
1
(0)

HP1γ shRNA Plasmid (m)

sc-35590-SHmGene SilencingPuromycin
1
(0)

HP1γ shRNA (m) Lentiviral Particles

sc-35590-VmGene SilencingPuromycin
1
(0)