Date published: 2025-10-15

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HP1 β Antibodies

Santa Cruz Biotechnology provides a broad selection of HP1 β monoclonal antibodies for investigating this crucial chromatin protein. The monoclonal antibodies are validated for western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HP1 β is a key component of heterochromatin, playing a significant role in gene regulation, chromatin structure, and maintaining genomic stability. Its involvement in cellular processes such as transcriptional repression and DNA repair highlights its importance in both normal cellular function and disease states, including cancer. Understanding the dynamics of HP1 β provides essential insights into epigenetic regulation mechanisms. Researchers can explore how HP1 β influences chromatin organization and gene expression patterns across different cell types. Advanced research with HP1 β monoclonal antibodies reveals new pathways in DNA damage response and cell cycle regulation. The high specificity of Santa Cruz Biotechnology monoclonal antibodies enables researchers worldwide to advance scientific understanding of chromatin biology and epigenetic mechanisms.

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HP1 β Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

HP1β Antibody (4D7B8)

sc-517288mouse IgG1 κFL (h)WB, IP, IF, IHC(P), FCM, ELISAm, r, h
3
(2)

HP1β Antibody (MAC353)

sc-56704rat IgG2bC-Terminal (m)WB, IP, IFm, r, h

new

(4)

HP1 β CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HP1β CRISPR/Cas9 KO Plasmid (h)

sc-403235hGene KnockoutGFP0
(0)

HP1β CRISPR/Cas9 KO Plasmid (h2)

sc-403235-KO-2hGene KnockoutGFP0
(0)

HP1β Double Nickase Plasmid (h)

sc-403235-NIChGene KnockoutPuromycin0
(0)

HP1β Double Nickase Plasmid (h2)

sc-403235-NIC-2hGene KnockoutPuromycin0
(0)

HP1β CRISPR/Cas9 KO Plasmid (m)

sc-419497mGene KnockoutGFP0
(0)

HP1β HDR Plasmid (m)

sc-419497-HDRmHomology Directed RepairPuromycin0
(0)

HP1β Double Nickase Plasmid (m)

sc-419497-NICmGene KnockoutPuromycin0
(0)

HP1β Double Nickase Plasmid (m2)

sc-419497-NIC-2mGene KnockoutPuromycin0
(0)

HP1HP1β HDR Plasmid (h2)

sc-403235-HDR-2hHomology Directed RepairPuromycin0
(0)

HP1 β CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HP1β CRISPR Activation Plasmid (h)

sc-403235-ACThGene ActivationPuro, Blast, Hygro0
(0)

HP1β CRISPR Activation Plasmid (h2)

sc-403235-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

HP1β Lentiviral Activation Particles (h)

sc-403235-LAChGene ActivationPuro, Blast, Hygro0
(0)

HP1β Lentiviral Activation Particles (h2)

sc-403235-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

HP1β CRISPR Activation Plasmid (m)

sc-419497-ACTmGene ActivationPuro, Blast, Hygro0
(0)

HP1β CRISPR Activation Plasmid (m2)

sc-419497-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

HP1β Lentiviral Activation Particles (m)

sc-419497-LACmGene ActivationPuro, Blast, Hygro0
(0)

HP1β Lentiviral Activation Particles (m2)

sc-419497-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

HP1 β siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

HP1β siRNA (h)

sc-35587hGene SilencingN/A0
(0)

HP1β shRNA Plasmid (h)

sc-35587-SHhGene SilencingPuromycin0
(0)

HP1β shRNA (h) Lentiviral Particles

sc-35587-VhGene SilencingPuromycin0
(0)

HP1β siRNA (m)

sc-35588mGene SilencingN/A
2
(0)

HP1β shRNA Plasmid (m)

sc-35588-SHmGene SilencingPuromycin
2
(0)

HP1β shRNA (m) Lentiviral Particles

sc-35588-VmGene SilencingPuromycin
2
(0)