Cyclin J Activators are a class of chemical compounds meticulously selected to enhance the functional activity of cyclin J (CCNJ). Cyclin J, a protein intricately involved in cell cycle regulation and various cellular processes, can be indirectly activated through the careful modulation of specific signaling pathways and biological processes. These activators, such as Resveratrol, exert their influence on cyclin J through the SIRT1 pathway, enhancing cell cycle regulation and cellular functions governed by cyclin J. Fasudil, on the other hand, enhances cyclin J's function by modulating Rho-associated protein kinase (ROCK), impacting cellular processes where cyclin J plays a vital role. Quercetin activates cyclin J indirectly by influencing the AMPK signaling pathway, promoting its involvement in cell cycle regulation and other cellular functions. SB216763 boosts cyclin J's function by inhibiting GSK-3β, indirectly affecting cellular processes linked to cyclin J. Additionally, compounds like MK-2206 enhance cyclin J activity by inhibiting Akt, a protein closely connected to cyclin J-regulated cellular functions and cell cycle regulation. PD98059 activates cyclin J by inhibiting MEK1/2 and subsequently promoting MAPK signaling, which is intricately linked with cyclin J's functions.
Furthermore, Y-27632 boosts cyclin J's activity by inhibiting Rho-associated protein kinase (ROCK), indirectly influencing cellular processes where cyclin J is a key player. Hesperidin enhances cyclin J function by indirectly affecting the PI3K/Akt pathway, which plays a crucial role in cellular processes associated with cyclin J. NSC 66811 activates cyclin J by influencing the Wnt signaling pathway, which intersects with cyclin J-regulated cellular functions and cell cycle regulation. BI-2536, through its impact on Plk1, enhances cyclin J's activity, particularly in cellular processes like cell cycle progression. AZD8055 boosts cyclin J function by inhibiting mTOR, indirectly affecting cellular processes linked to cyclin J. Finally, Naringenin activates cyclin J through the AMPK signaling pathway, indirectly promoting its role in cell cycle regulation and various cellular functions. In summary, Cyclin J Activators represent a versatile set of compounds that offer precise tools for researchers aiming to explore the roles of cyclin J in cell biology and cell cycle regulation.
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| Nombre del producto | NÚMERO DE CAS # | Número de catálogo | Cantidad | Precio | MENCIONES | Clasificación |
|---|---|---|---|---|---|---|
PD 98059 | 167869-21-8 | sc-3532 sc-3532A | 1 mg 5 mg | $39.00 $90.00 | 212 | |
Inhibe MEK, lo que puede afectar a las cascadas de señalización relevantes para la función de STYX. | ||||||
Hesperidin | 520-26-3 | sc-205711 sc-205711A | 25 g 100 g | $80.00 $200.00 | 5 | |
Potencia la función de la ciclina J al afectar indirectamente a la vía PI3K/Akt, que desempeña un papel en los procesos celulares asociados a la ciclina J. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $62.00 $155.00 $320.00 | 233 | |
Inhibe mTOR, lo que puede influir en las vías de señalización y los procesos celulares en los que STYX está implicado. | ||||||
NSC 66811 | 6964-62-1 | sc-311507 sc-311507A | 10 mg 50 mg | $159.00 $670.00 | ||
Activa la ciclina J influyendo en la vía de señalización Wnt, que se cruza con las funciones celulares reguladas por la ciclina J y la regulación del ciclo celular. | ||||||
Triciribine | 35943-35-2 | sc-200661 sc-200661A | 1 mg 5 mg | $102.00 $138.00 | 14 | |
Inhibe AKT, afectando a la actividad de las vías de señalización descendentes que implican a STYX. | ||||||
Bisindolylmaleimide I (GF 109203X) | 133052-90-1 | sc-24003A sc-24003 | 1 mg 5 mg | $103.00 $237.00 | 36 | |
Inhibe la proteína quinasa C, alterando las vías de señalización que STYX puede modular. | ||||||
BI 2536 | 755038-02-9 | sc-364431 sc-364431A | 5 mg 50 mg | $148.00 $515.00 | 8 | |
Potencia la actividad de la ciclina J dirigiéndose a Plk1, una proteína implicada en procesos celulares regulados por la ciclina J, como la progresión del ciclo celular. | ||||||
AZD8055 | 1009298-09-2 | sc-364424 sc-364424A | 10 mg 50 mg | $160.00 $345.00 | 12 | |
Renforce la fonction de la cycline J en inhibant mTOR, affectant indirectement les processus cellulaires liés à la cycline J. | ||||||
Gö 6983 | 133053-19-7 | sc-203432 sc-203432A sc-203432B | 1 mg 5 mg 10 mg | $103.00 $293.00 $465.00 | 15 | |
Inhibe una amplia gama de isoformas PKC, afectando a vías en las que STYX está implicada. | ||||||
Dasatinib | 302962-49-8 | sc-358114 sc-358114A | 25 mg 1 g | $47.00 $145.00 | 51 | |
Inhibe las quinasas de la familia Src y otras tirosina quinasas, alterando los procesos de señalización relacionados con STYX. | ||||||