Date published: 2025-9-7

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cyclin J Activadores

Cyclin J Activators are a class of chemical compounds meticulously selected to enhance the functional activity of cyclin J (CCNJ). Cyclin J, a protein intricately involved in cell cycle regulation and various cellular processes, can be indirectly activated through the careful modulation of specific signaling pathways and biological processes. These activators, such as Resveratrol, exert their influence on cyclin J through the SIRT1 pathway, enhancing cell cycle regulation and cellular functions governed by cyclin J. Fasudil, on the other hand, enhances cyclin J's function by modulating Rho-associated protein kinase (ROCK), impacting cellular processes where cyclin J plays a vital role. Quercetin activates cyclin J indirectly by influencing the AMPK signaling pathway, promoting its involvement in cell cycle regulation and other cellular functions. SB216763 boosts cyclin J's function by inhibiting GSK-3β, indirectly affecting cellular processes linked to cyclin J. Additionally, compounds like MK-2206 enhance cyclin J activity by inhibiting Akt, a protein closely connected to cyclin J-regulated cellular functions and cell cycle regulation. PD98059 activates cyclin J by inhibiting MEK1/2 and subsequently promoting MAPK signaling, which is intricately linked with cyclin J's functions.

Furthermore, Y-27632 boosts cyclin J's activity by inhibiting Rho-associated protein kinase (ROCK), indirectly influencing cellular processes where cyclin J is a key player. Hesperidin enhances cyclin J function by indirectly affecting the PI3K/Akt pathway, which plays a crucial role in cellular processes associated with cyclin J. NSC 66811 activates cyclin J by influencing the Wnt signaling pathway, which intersects with cyclin J-regulated cellular functions and cell cycle regulation. BI-2536, through its impact on Plk1, enhances cyclin J's activity, particularly in cellular processes like cell cycle progression. AZD8055 boosts cyclin J function by inhibiting mTOR, indirectly affecting cellular processes linked to cyclin J. Finally, Naringenin activates cyclin J through the AMPK signaling pathway, indirectly promoting its role in cell cycle regulation and various cellular functions. In summary, Cyclin J Activators represent a versatile set of compounds that offer precise tools for researchers aiming to explore the roles of cyclin J in cell biology and cell cycle regulation.

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Nombre del productoNÚMERO DE CAS #Número de catálogoCantidadPrecioMENCIONESClasificación

PP 2

172889-27-9sc-202769
sc-202769A
1 mg
5 mg
$92.00
$223.00
30
(1)

Inhibe las quinasas de la familia Src, alterando potencialmente el estado de fosforilación de las proteínas que interactúan con STYX.

Resveratrol

501-36-0sc-200808
sc-200808A
sc-200808B
100 mg
500 mg
5 g
$60.00
$185.00
$365.00
64
(2)

Activa la ciclina J indirectamente influyendo en la vía SIRT1, lo que conduce a una mayor regulación del ciclo celular y de las funciones celulares que implican a la ciclina J.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$121.00
$392.00
148
(1)

Inhibe PI3K, lo que puede afectar a las vías de señalización descendentes en las que participa STYX.

Quercetin

117-39-5sc-206089
sc-206089A
sc-206089E
sc-206089C
sc-206089D
sc-206089B
100 mg
500 mg
100 g
250 g
1 kg
25 g
$11.00
$17.00
$108.00
$245.00
$918.00
$49.00
33
(2)

Activa la ciclina J a través de la vía de señalización AMPK, promoviendo indirectamente su papel en la regulación del ciclo celular y las funciones celulares.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$88.00
$342.00
284
(5)

Inhibe la p38 MAP cinasa, que puede modificar el contexto celular en el que actúa STYX.

SB-216763

280744-09-4sc-200646
sc-200646A
1 mg
5 mg
$70.00
$198.00
18
(1)

Potencia la función de la ciclina J mediante la inhibición de GSK-3β, afectando indirectamente a los procesos celulares en los que la ciclina J desempeña un papel clave.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$65.00
$267.00
257
(3)

Inhibe JNK, que puede afectar a las vías de señalización vinculadas a STYX.

MK-2206 dihydrochloride

1032350-13-2sc-364537
sc-364537A
5 mg
10 mg
$178.00
$325.00
67
(1)

Potencia la actividad de la ciclina J mediante la inhibición de Akt, una proteína relacionada con las funciones celulares reguladas por la ciclina J y la regulación del ciclo celular.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$66.00
$219.00
$417.00
97
(3)

Inhibe la PI3K, afectando a las vías de señalización y a las interacciones proteicas en las que interviene STYX.

Y-27632, free base

146986-50-7sc-3536
sc-3536A
5 mg
50 mg
$182.00
$693.00
88
(1)

Potencia la actividad de la ciclina J inhibiendo la proteína cinasa asociada a Rho (ROCK), lo que afecta indirectamente a los procesos celulares en los que interviene la ciclina J.