Date published: 2025-9-9

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Polycystin Antikörper und Ähnliche Produkte

Santa Cruz Biotechnology bietet eine Vielzahl von monoklonalen Polycystin-Antikörpern zur Untersuchung von Polycystinen, integralen Membranproteinen, die für die Nierenfunktion und die zelluläre Signalübertragung entscheidend sind. Die monoklonalen Polycystin-Antikörper sind mit verschiedenen Forschungstechniken kompatibel, darunter Western Blotting (WB), Immunpräzipitation (IP), Immunfluoreszenz (IF), Immunhistochemie mit Paraffin eingebetteten Schnitten (IHCP), Durchflusszytometrie (FCM) und Enzyme-Linked Immunosorbent Assay (ELISA). Polycystine spielen eine wichtige Rolle bei der Regulierung der Zellproliferation, der Differenzierung und der Aufrechterhaltung der Architektur der Nierentubuli. Eine Fehlregulierung der Polycystinfunktion wird mit der polyzystischen Nierenerkrankung (PKD) in Verbindung gebracht, einer genetischen Störung, die zur Bildung von Zysten in den Nieren führt und zu Nierenversagen führen kann. Das Verständnis der Polycystin-Mechanismen ist für die Entwicklung therapeutischer Strategien für PKD und verwandte Erkrankungen von entscheidender Bedeutung. Die Polycystin-Forschung hat wichtige Erkenntnisse über die Entwicklung der Niere und das Fortschreiten der Krankheit erbracht. Laufende Studien decken weiterhin neue Funktionen und Regulationswege auf, an denen Polycystine in der zellulären Homöostase beteiligt sind. Die aktuelle Forschung konzentriert sich auf die Identifizierung potenzieller therapeutischer Ziele für die Behandlung von PKD durch eine detaillierte Analyse der Polycystin-Signalwege. Die monoklonalen Antikörper von Santa Cruz Biotechnology unterstützen Forscher auf der ganzen Welt dabei, das wissenschaftliche Wissen über Polycystine und ihre Rolle bei Nierengesundheit und -erkrankungen zu erweitern.

Siehe auch...

Polycystin Antikörper

Empty Table HeaderProduktKatnr.IsotypEpitopAnwendungenSpeciesReferenzenBewertung

Polycystin-1 Antikörper (7E12)

sc-130554mouse IgG1 κ24-180 (h)WB, IP, IF, ELISAm, r, h
63
(8)

Polycystin-2 Antikörper (YCE2)

sc-47734mouse IgG2a κ687-754 (h)WB, IP, IF, IHC(P)m, r, h
21
(9)

Polycystin-2 Antikörper (D-3)

sc-28331mouse IgG2b κ689-968 (h)WB, IP, IF, IHC(P), ELISAm, r, h
33
(10)

Polycystin CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduktKatnr.SpeciesAnwendungenMARKERReferenzenBewertung

Polycystin-L CRISPR/Cas9 KO Plasmid (h)

sc-408701hGene KnockoutGFP0
(0)

Polycystin-L HDR Plasmid (h)

sc-408701-HDRhHomology Directed RepairPuromycin0
(0)

Polycystin-L Double Nickase Plasmid (h)

sc-408701-NIChGene KnockoutPuromycin0
(0)

Polycystin-L Double Nickase Plasmid (h2)

sc-408701-NIC-2hGene KnockoutPuromycin0
(0)

Polycystin-L CRISPR/Cas9 KO Plasmid (m)

sc-435928mGene KnockoutGFP0
(0)

Polycystin-L HDR Plasmid (m)

sc-435928-HDRmHomology Directed RepairPuromycin0
(0)

Polycystin-L Double Nickase Plasmid (m)

sc-435928-NICmGene KnockoutPuromycin0
(0)

Polycystin-L Double Nickase Plasmid (m2)

sc-435928-NIC-2mGene KnockoutPuromycin0
(0)

Polycystin-1 Double Nickase Plasmid (h)

sc-400983-NIChGene KnockoutPuromycin0
(0)

Polycystin-1 Double Nickase Plasmid (h2)

sc-400983-NIC-2hGene KnockoutPuromycin0
(0)

Polycystin-1 CRISPR/Cas9 KO Plasmid (m2)

sc-422267-KO-2mGene KnockoutGFP0
(0)

Polycystin-1 HDR Plasmid (m2)

sc-422267-HDR-2mHomology Directed RepairPuromycin0
(0)

Polycystin-1 Double Nickase Plasmid (m)

sc-422267-NICmGene KnockoutPuromycin0
(0)

Polycystin-1 Double Nickase Plasmid (m2)

sc-422267-NIC-2mGene KnockoutPuromycin0
(0)

Polycystin-2 CRISPR/Cas9 KO Plasmid (h)

sc-400669hGene KnockoutGFP0
(0)

Polycystin-2 HDR Plasmid (h2)

sc-400669-HDR-2hHomology Directed RepairPuromycin0
(0)

Polycystin-2 Double Nickase Plasmid (h)

sc-400669-NIChGene KnockoutPuromycin0
(0)

Polycystin-2 Double Nickase Plasmid (h2)

sc-400669-NIC-2hGene KnockoutPuromycin0
(0)

Polycystin-2 CRISPR/Cas9 KO Plasmid (m2)

sc-422268-KO-2mGene KnockoutGFP0
(0)

Polycystin-2 Double Nickase Plasmid (m)

sc-422268-NICmGene KnockoutPuromycin0
(0)

Polycystin-2 Double Nickase Plasmid (m2)

sc-422268-NIC-2mGene KnockoutPuromycin0
(0)

Polycystin-L2 CRISPR/Cas9 KO Plasmid (h)

sc-411949hGene KnockoutGFP0
(0)

Polycystin-L2 HDR Plasmid (h)

sc-411949-HDRhHomology Directed RepairPuromycin0
(0)

Polycystin-L2 Double Nickase Plasmid (h)

sc-411949-NIChGene KnockoutPuromycin0
(0)

Polycystin-L2 Double Nickase Plasmid (h2)

sc-411949-NIC-2hGene KnockoutPuromycin0
(0)

Polycystin-L2 CRISPR/Cas9 KO Plasmid (m)

sc-424756mGene KnockoutGFP0
(0)

Polycystin-L2 HDR Plasmid (m)

sc-424756-HDRmHomology Directed RepairPuromycin0
(0)

Polycystin-L2 Double Nickase Plasmid (m)

sc-424756-NICmGene KnockoutPuromycin0
(0)

Polycystin-L2 Double Nickase Plasmid (m2)

sc-424756-NIC-2mGene KnockoutPuromycin0
(0)

Polycystin-1L1 CRISPR/Cas9 KO Plasmid (h)

sc-414908hGene KnockoutGFP0
(0)

Polycystin-1L1 HDR Plasmid (h)

sc-414908-HDRhHomology Directed RepairPuromycin0
(0)

Polycystin-1L1 Double Nickase Plasmid (h)

sc-414908-NIChGene KnockoutPuromycin0
(0)

Polycystin-1L1 Double Nickase Plasmid (h2)

sc-414908-NIC-2hGene KnockoutPuromycin0
(0)

Polycystin-1L2 CRISPR/Cas9 KO Plasmid (h)

sc-414038hGene KnockoutGFP0
(0)

Polycystin-1L2 HDR Plasmid (h)

sc-414038-HDRhHomology Directed RepairPuromycin0
(0)

Polycystin-1L2 Double Nickase Plasmid (h)

sc-414038-NIChGene KnockoutPuromycin0
(0)

Polycystin-1L2 Double Nickase Plasmid (h2)

sc-414038-NIC-2hGene KnockoutPuromycin0
(0)

Polycystin-1L2 CRISPR/Cas9 KO Plasmid (m)

sc-429384mGene KnockoutGFP0
(0)

Polycystin-1L2 HDR Plasmid (m)

sc-429384-HDRmHomology Directed RepairPuromycin0
(0)

Polycystin-1L2 Double Nickase Plasmid (m)

sc-429384-NICmGene KnockoutPuromycin0
(0)

Polycystin-1L2 Double Nickase Plasmid (m2)

sc-429384-NIC-2mGene KnockoutPuromycin0
(0)

Polycystin-1L3 CRISPR/Cas9 KO Plasmid (h)

sc-409096hGene KnockoutGFP0
(0)

Polycystin-1L3 HDR Plasmid (h)

sc-409096-HDRhHomology Directed RepairPuromycin0
(0)

Polycystin-1L3 Double Nickase Plasmid (h)

sc-409096-NIChGene KnockoutPuromycin0
(0)

Polycystin-1L3 Double Nickase Plasmid (h2)

sc-409096-NIC-2hGene KnockoutPuromycin0
(0)

Polycystin-1L3 CRISPR/Cas9 KO Plasmid (m)

sc-434082mGene KnockoutGFP0
(0)

Polycystin-1L3 HDR Plasmid (m)

sc-434082-HDRmHomology Directed RepairPuromycin0
(0)

Polycystin-1L3 Double Nickase Plasmid (m)

sc-434082-NICmGene KnockoutPuromycin0
(0)

Polycystin-1L3 Double Nickase Plasmid (m2)

sc-434082-NIC-2mGene KnockoutPuromycin0
(0)

Polycystin CRISPR Activation Products

Empty Table HeaderProduktKatnr.SpeciesAnwendungenMARKERReferenzenBewertung

Polycystin-L CRISPR Activation Plasmid (h)

sc-408701-ACThGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L CRISPR Activation Plasmid (h2)

sc-408701-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L Lentiviral Activation Particles (h)

sc-408701-LAChGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L Lentiviral Activation Particles (h2)

sc-408701-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L CRISPR Activation Plasmid (m)

sc-435928-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L CRISPR Activation Plasmid (m2)

sc-435928-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L Lentiviral Activation Particles (m)

sc-435928-LACmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L Lentiviral Activation Particles (m2)

sc-435928-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 CRISPR Activation Plasmid (h)

sc-400983-ACThGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 CRISPR Activation Plasmid (h2)

sc-400983-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 Lentiviral Activation Particles (h)

sc-400983-LAChGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 Lentiviral Activation Particles (h2)

sc-400983-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 CRISPR Activation Plasmid (m)

sc-422267-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 CRISPR Activation Plasmid (m2)

sc-422267-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 Lentiviral Activation Particles (m)

sc-422267-LACmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1 Lentiviral Activation Particles (m2)

sc-422267-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 CRISPR Activation Plasmid (h)

sc-400669-ACThGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 CRISPR Activation Plasmid (h2)

sc-400669-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 Lentiviral Activation Particles (h)

sc-400669-LAChGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 Lentiviral Activation Particles (h2)

sc-400669-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 CRISPR Activation Plasmid (m)

sc-422268-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 CRISPR Activation Plasmid (m2)

sc-422268-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 Lentiviral Activation Particles (m)

sc-422268-LACmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-2 Lentiviral Activation Particles (m2)

sc-422268-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 CRISPR Activation Plasmid (h)

sc-411949-ACThGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 CRISPR Activation Plasmid (h2)

sc-411949-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 Lentiviral Activation Particles (h)

sc-411949-LAChGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 Lentiviral Activation Particles (h2)

sc-411949-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 CRISPR Activation Plasmid (m)

sc-424756-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 CRISPR Activation Plasmid (m2)

sc-424756-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 Lentiviral Activation Particles (m)

sc-424756-LACmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-L2 Lentiviral Activation Particles (m2)

sc-424756-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L1 CRISPR Activation Plasmid (h)

sc-414908-ACThGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L1 CRISPR Activation Plasmid (h2)

sc-414908-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L1 Lentiviral Activation Particles (h)

sc-414908-LAChGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L1 Lentiviral Activation Particles (h2)

sc-414908-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 CRISPR Activation Plasmid (h)

sc-414038-ACThGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 CRISPR Activation Plasmid (h2)

sc-414038-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 Lentiviral Activation Particles (h)

sc-414038-LAChGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 Lentiviral Activation Particles (h2)

sc-414038-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 CRISPR Activation Plasmid (m)

sc-429384-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 CRISPR Activation Plasmid (m2)

sc-429384-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 Lentiviral Activation Particles (m)

sc-429384-LACmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L2 Lentiviral Activation Particles (m2)

sc-429384-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 CRISPR Activation Plasmid (h)

sc-409096-ACThGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 CRISPR Activation Plasmid (h2)

sc-409096-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 Lentiviral Activation Particles (h)

sc-409096-LAChGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 Lentiviral Activation Particles (h2)

sc-409096-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 CRISPR Activation Plasmid (m)

sc-434082-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 CRISPR Activation Plasmid (m2)

sc-434082-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 Lentiviral Activation Particles (m)

sc-434082-LACmGene ActivationPuro, Blast, Hygro0
(0)

Polycystin-1L3 Lentiviral Activation Particles (m2)

sc-434082-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

Polycystin siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduktKatnr.SpeciesAnwendungenMARKERReferenzenBewertung

Polycystin-L siRNA (h)

sc-90835hGene SilencingN/A0
(0)

Polycystin-L shRNA Plasmid (h)

sc-90835-SHhGene SilencingPuromycin0
(0)

Polycystin-L shRNA (h) Lentivirale Partikel

sc-90835-VhGene SilencingPuromycin0
(0)

Polycystin-L siRNA (m)

sc-152386mGene SilencingN/A0
(0)

Polycystin-L shRNA Plasmid (m)

sc-152386-SHmGene SilencingPuromycin0
(0)

Polycystin-L shRNA (m) Lentivirale Partikel

sc-152386-VmGene SilencingPuromycin0
(0)

Polycystin-1 siRNA (h)

sc-40861hGene SilencingN/A
1
(0)

Polycystin-1 shRNA Plasmid (h)

sc-40861-SHhGene SilencingPuromycin
1
(0)

Polycystin-1 shRNA (h) Lentivirale Partikel

sc-40861-VhGene SilencingPuromycin
1
(0)

Polycystin-1 siRNA (m)

sc-40862mGene SilencingN/A
1
(0)

Polycystin-1 shRNA Plasmid (m)

sc-40862-SHmGene SilencingPuromycin
1
(0)

Polycystin-1 shRNA (m) Lentivirale Partikel

sc-40862-VmGene SilencingPuromycin
1
(0)

Polycystin-2 siRNA (h)

sc-40863hGene SilencingN/A0
(0)

Polycystin-2 shRNA Plasmid (h)

sc-40863-SHhGene SilencingPuromycin0
(0)

Polycystin-2 shRNA (h) Lentivirale Partikel

sc-40863-VhGene SilencingPuromycin0
(0)

Polycystin-2 siRNA (m)

sc-40864mGene SilencingN/A0
(0)

Polycystin-2 shRNA Plasmid (m)

sc-40864-SHmGene SilencingPuromycin0
(0)

Polycystin-2 shRNA (m) Lentivirale Partikel

sc-40864-VmGene SilencingPuromycin0
(0)

Polycystin-L2 siRNA (h)

sc-91892hGene SilencingN/A0
(0)

Polycystin-L2 shRNA Plasmid (h)

sc-91892-SHhGene SilencingPuromycin0
(0)

Polycystin-L2 shRNA (h) Lentivirale Partikel

sc-91892-VhGene SilencingPuromycin0
(0)

Polycystin-L2 siRNA (m)

sc-152387mGene SilencingN/A0
(0)

Polycystin-L2 shRNA Plasmid (m)

sc-152387-SHmGene SilencingPuromycin0
(0)

Polycystin-L2 shRNA (m) Lentivirale Partikel

sc-152387-VmGene SilencingPuromycin0
(0)

Polycystin-1L1 siRNA (h)

sc-89442hGene SilencingN/A0
(0)

Polycystin-1L1 shRNA Plasmid (h)

sc-89442-SHhGene SilencingPuromycin0
(0)

Polycystin-1L1 shRNA (h) Lentivirale Partikel

sc-89442-VhGene SilencingPuromycin0
(0)

Polycystin-1L1 siRNA (m)

sc-152383mGene SilencingN/A0
(0)

Polycystin-1L1 shRNA Plasmid (m)

sc-152383-SHmGene SilencingPuromycin0
(0)

Polycystin-1L1 shRNA (m) Lentivirale Partikel

sc-152383-VmGene SilencingPuromycin0
(0)

Polycystin-1L2 siRNA (h)

sc-93058hGene SilencingN/A0
(0)

Polycystin-1L2 shRNA Plasmid (h)

sc-93058-SHhGene SilencingPuromycin0
(0)

Polycystin-1L2 shRNA (h) Lentivirale Partikel

sc-93058-VhGene SilencingPuromycin0
(0)

Polycystin-1L2 siRNA (m)

sc-152384mGene SilencingN/A0
(0)

Polycystin-1L2 shRNA Plasmid (m)

sc-152384-SHmGene SilencingPuromycin0
(0)

Polycystin-1L2 shRNA (m) Lentivirale Partikel

sc-152384-VmGene SilencingPuromycin0
(0)

Polycystin-1L3 siRNA (h)

sc-93309hGene SilencingN/A0
(0)

Polycystin-1L3 shRNA Plasmid (h)

sc-93309-SHhGene SilencingPuromycin0
(0)

Polycystin-1L3 shRNA (h) Lentivirale Partikel

sc-93309-VhGene SilencingPuromycin0
(0)

Polycystin-1L3 siRNA (m)

sc-152385mGene SilencingN/A0
(0)

Polycystin-1L3 shRNA Plasmid (m)

sc-152385-SHmGene SilencingPuromycin0
(0)

Polycystin-1L3 shRNA (m) Lentivirale Partikel

sc-152385-VmGene SilencingPuromycin0
(0)