Polycystin-2 Antibodies

Santa Cruz Biotechnology offers a broad range of Polycystin-2 monoclonal antibodies for research focused on understanding cellular signaling and renal function. Polycystin-2 Antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Polycystin-2, also known as PKD2, functions as a vital component of the polycystin complex, with significant implications in renal function and cellular signaling pathways. Mutations in the PKD2 gene are associated with autosomal dominant polycystic kidney disease (ADPKD), highlighting its importance in kidney health and disease. Research has shown that Polycystin-2 interacts with various cellular components to regulate calcium homeostasis and mechanosensation. Understanding the molecular mechanisms of Polycystin-2 can provide valuable insights into the development of targeted therapies for kidney disorders. Recent studies have revealed new roles for Polycystin-2 in cellular processes beyond kidney function, including cardiac development and cell cycle regulation. Santa Cruz Biotechnology monoclonal antibodies enable researchers worldwide to advance scientific understanding of Polycystin-2 and its role in human health and disease.