Date published: 2026-5-25

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HDAC6 Antibodies

Santa Cruz Biotechnology provides a broad selection of HDAC6 monoclonal antibodies for research focused on understanding histone deacetylase 6 in various biological processes. HDAC6 monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). HDAC6 is a crucial enzyme involved in the regulation of gene expression, protein stability, and cellular stress responses. As a unique cytoplasmic deacetylase, HDAC6 influences cell migration, immune response, and neurodegeneration through its ability to modify non-histone proteins. Understanding HDAC6 function is essential for advancing research in cancer biology, neurodegenerative disorders, and various pathological conditions. Researchers worldwide utilize HDAC6 monoclonal antibodies to investigate cellular pathways and molecular mechanisms. Current studies with HDAC6 monoclonal antibodies are uncovering new insights into therapeutic strategies for various diseases. HDAC6 monoclonal antibodies enable precise detection and analysis of protein interactions and modifications in cellular systems. Santa Cruz Biotechnology monoclonal antibodies for HDAC6 continue to support breakthrough discoveries in biomedical research and therapeutic development.

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HDAC6 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

Histone Deacetylase 6 Antibody (D-11)

sc-28386mouse IgG2a κ916-1215 (h)WB, IP, IF, IHC(P), ELISAh
51
(16)

HDAC6 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Histone Deacetylase 6 (HDAC6) CRISPR/Cas9 KO Plasmid (h2)

sc-400314-KO-2hGene KnockoutGFP
1
(0)

Histone Deacetylase 6 (HDAC6) HDR Plasmid (h2)

sc-400314-HDR-2hHomology Directed RepairPuromycin
1
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (h)

sc-400314-NIChGene KnockoutPuromycin
1
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (h2)

sc-400314-NIC-2hGene KnockoutPuromycin
1
(0)

Histone Deacetylase 6 (HDAC6) CRISPR/Cas9 KO Plasmid (m)

sc-420820mGene KnockoutGFP0
(0)

Histone Deacetylase 6 (HDAC6) HDR Plasmid (m)

sc-420820-HDRmHomology Directed RepairPuromycin0
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (m)

sc-420820-NICmGene KnockoutPuromycin0
(0)

Histone Deacetylase 6 (HDAC6) Double Nickase Plasmid (m2)

sc-420820-NIC-2mGene KnockoutPuromycin0
(0)

HDAC6 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (h)

sc-400314-ACThGene ActivationPuro, Blast, Hygro
1
(0)

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (h2)

sc-400314-ACT-2hGene ActivationPuro, Blast, Hygro
1
(0)

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (m)

sc-420820-ACTmGene ActivationPuro, Blast, Hygro0
(0)

Histone Deacetylase 6 (HDAC6) CRISPR Activation Plasmid (m2)

sc-420820-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

Histone Deacetylase 6 (HDAC6) Lentiviral Activation Particles (m)

sc-420820-LACmGene ActivationPuro, Blast, Hygro0
(0)

HDAC6 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

Histone Deacetylase 6 (HDAC6) siRNA (h)

sc-35544hGene SilencingN/A
28
(0)

Histone Deacetylase 6 (HDAC6) shRNA Plasmid (h)

sc-35544-SHhGene SilencingPuromycin
28
(0)

Histone Deacetylase 6 (HDAC6) shRNA (h) Lentiviral Particles

sc-35544-VhGene SilencingPuromycin
28
(0)

Histone Deacetylase 6 (HDAC6) siRNA (m)

sc-35545mGene SilencingN/A
7
(1)

Histone Deacetylase 6 (HDAC6) shRNA Plasmid (m)

sc-35545-SHmGene SilencingPuromycin
7
(1)

Histone Deacetylase 6 (HDAC6) shRNA (m) Lentiviral Particles

sc-35545-VmGene SilencingPuromycin
7
(1)