Date published: 2025-12-17

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ZXDB Inhibitors

ZXDB inhibitors represent a class of chemical compounds that specifically target the ZXDB protein, a crucial element in a variety of biological systems due to its involvement in cellular regulation and transcriptional control. ZXDB is known to function as a transcriptional regulator, influencing gene expression and cellular signaling pathways. Compounds classified as ZXDB inhibitors act by binding to the active sites of this protein, altering its conformation and preventing its usual biological activity. The structural diversity of these inhibitors often includes small molecules featuring heterocyclic cores, which are functionalized to enhance specificity for ZXDB. The selectivity of these inhibitors is key, as they aim to block the protein's activity without impacting other proteins within the cell, making their development a challenging but scientifically significant pursuit.

The mechanisms of ZXDB inhibition vary depending on the structural attributes of the inhibitor and the molecular features of the binding site. Many of these compounds rely on hydrophobic interactions and hydrogen bonding to establish a strong interaction with the ZXDB protein. Additionally, some inhibitors may engage in covalent bonding with certain amino acids within the active site, leading to irreversible inhibition. Understanding the physicochemical properties of ZXDB inhibitors, such as their solubility, molecular weight, and lipophilicity, is crucial for predicting their behavior in complex biological environments. Extensive research is devoted to elucidating the binding dynamics between ZXDB and its inhibitors, which often involves computational modeling, crystallography, and biophysical techniques to characterize the precise interactions at the molecular level.

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Items 11 to 12 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Disulfiram

97-77-8sc-205654
sc-205654A
50 g
100 g
$52.00
$87.00
7
(1)

Disulfiram could inhibit the activity of certain transcription factors or histone modifying enzymes through the chelation of trace metal ions, potentially leading to a decrease in ZXDB expression by altering the chromatin state or transcription factor availability at the ZXDB locus.

Flavopiridol

146426-40-6sc-202157
sc-202157A
5 mg
25 mg
$78.00
$254.00
41
(3)

This cyclin-dependent kinase inhibitor might downregulate the expression of ZXDB by inhibiting the phosphorylation of proteins involved in the regulation of transcription initiation and elongation, potentially leading to a reduction in the rate of ZXDB transcription.