Date published: 2025-12-7

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ZO-2 Antibodies

Santa Cruz Biotechnology features a diverse variety of ZO-2 monoclonal antibodies for research focused on understanding ZO-2 protein function. The monoclonal antibodies are validated for multiple applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). ZO-2, also known as Zonula Occludens-2, is a critical component of tight junctions in epithelial and endothelial cells, playing a vital role in maintaining cell polarity and barrier function. ZO-2 regulates paracellular permeability and is essential for proper tissue and organ function. Research has shown that ZO-2 alterations are linked to various diseases, including cancer and inflammatory disorders. Understanding ZO-2's molecular mechanisms and cellular functions continues to be an active area of investigation in cell biology and disease research. Exploring ZO-2's role in tight junction assembly and regulation can provide insights into potential therapeutic strategies. Current research focuses on how ZO-2 interacts with other junction proteins and its signaling pathways. Santa Cruz Biotechnology monoclonal antibodies enable researchers to advance scientific understanding of ZO-2's role in health and disease.

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ZO-2 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ZO-2 Antibody (E-3)

sc-515115mouse IgM κ789-813 (r)WB, IP, IF, ELISAm, r, h
5
(6)

ZO-2 Antibody (E-5)

sc-514557mouse IgG1 κ1145-1167 (h)WB, IP, IF, ELISAh

new

(0)

ZO-2 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ZO-2 CRISPR/Cas9 KO Plasmid (h)

sc-401395hGene KnockoutGFP0
(0)

ZO-2 HDR Plasmid (h)

sc-401395-HDRhHomology Directed RepairPuromycin0
(0)

ZO-2 Double Nickase Plasmid (h)

sc-401395-NIChGene KnockoutPuromycin0
(0)

ZO-2 Double Nickase Plasmid (h2)

sc-401395-NIC-2hGene KnockoutPuromycin0
(0)

ZO-2 CRISPR/Cas9 KO Plasmid (m)

sc-423408mGene KnockoutGFP0
(0)

ZO-2 HDR Plasmid (m)

sc-423408-HDRmHomology Directed RepairPuromycin0
(0)

ZO-2 Double Nickase Plasmid (m)

sc-423408-NICmGene KnockoutPuromycin0
(0)

ZO-2 Double Nickase Plasmid (m2)

sc-423408-NIC-2mGene KnockoutPuromycin0
(0)

ZO-2 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ZO-2 CRISPR Activation Plasmid (h)

sc-401395-ACThGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 CRISPR Activation Plasmid (h2)

sc-401395-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 Lentiviral Activation Particles (h)

sc-401395-LAChGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 Lentiviral Activation Particles (h2)

sc-401395-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 CRISPR Activation Plasmid (m)

sc-423408-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 CRISPR Activation Plasmid (m2)

sc-423408-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 Lentiviral Activation Particles (m)

sc-423408-LACmGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 Lentiviral Activation Particles (m2)

sc-423408-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ZO-2 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ZO-2 siRNA (h)

sc-29833hGene SilencingN/A
2
(1)

ZO-2 shRNA Plasmid (h)

sc-29833-SHhGene SilencingPuromycin
2
(1)

ZO-2 shRNA (h) Lentiviral Particles

sc-29833-VhGene SilencingPuromycin
2
(1)

ZO-2 siRNA (m)

sc-29926mGene SilencingN/A0
(0)

ZO-2 shRNA Plasmid (m)

sc-29926-SHmGene SilencingPuromycin0
(0)

ZO-2 shRNA (m) Lentiviral Particles

sc-29926-VmGene SilencingPuromycin0
(0)