Date published: 2025-10-4

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ZO-3 Antibodies

Santa Cruz Biotechnology offers a broad range of ZO-3 monoclonal antibodies for research in cell adhesion and tight junction formation. ZO-3 monoclonal antibodies are compatible with multiple research applications, including western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). ZO-3, a crucial component of tight junctions, plays a significant role in maintaining the integrity of epithelial and endothelial barriers. By regulating paracellular permeability, ZO-3 is essential for tissue homeostasis and cellular communication. ZO-3 has been extensively studied in relation to cancer development, inflammatory responses, and various pathological conditions. Understanding ZO-3's molecular interactions and regulatory mechanisms can provide valuable insights into barrier function and tissue organization. Investigating ZO-3's role in different cellular processes helps reveal potential therapeutic targets. Research utilizing ZO-3 monoclonal antibodies continues to advance scientific understanding of cellular barriers and disease mechanisms. Santa Cruz Biotechnology monoclonal antibodies support researchers worldwide in uncovering new insights about ZO-3's functions in health and disease.

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ZO-3 Antibodies

Empty Table HeaderProduct NameCATALOG #ISOTYPEEPITOPEAPPLICATIONSSpeciesCitationsRATING

ZO-3 Antibody (1E8)

sc-293313mouse IgG2a κ868-952 (h)WB, IP, ELISAh

new

(2)

ZO-3 CRISPR Knockout, HDR and Double Nickase Plasmids

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ZO-3 CRISPR/Cas9 KO Plasmid (h)

sc-417338hGene KnockoutGFP0
(0)

ZO-3 HDR Plasmid (h)

sc-417338-HDRhHomology Directed RepairPuromycin0
(0)

ZO-3 Double Nickase Plasmid (h)

sc-417338-NIChGene KnockoutPuromycin0
(0)

ZO-3 Double Nickase Plasmid (h2)

sc-417338-NIC-2hGene KnockoutPuromycin0
(0)

ZO-3 CRISPR/Cas9 KO Plasmid (m)

sc-424246mGene KnockoutGFP0
(0)

ZO-3 HDR Plasmid (m)

sc-424246-HDRmHomology Directed RepairPuromycin0
(0)

ZO-3 Double Nickase Plasmid (m)

sc-424246-NICmGene KnockoutPuromycin0
(0)

ZO-3 Double Nickase Plasmid (m2)

sc-424246-NIC-2mGene KnockoutPuromycin0
(0)

ZO-3 CRISPR Activation Products

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ZO-3 CRISPR Activation Plasmid (h)

sc-417338-ACThGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 CRISPR Activation Plasmid (h2)

sc-417338-ACT-2hGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 Lentiviral Activation Particles (h)

sc-417338-LAChGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 Lentiviral Activation Particles (h2)

sc-417338-LAC-2hGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 CRISPR Activation Plasmid (m)

sc-424246-ACTmGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 CRISPR Activation Plasmid (m2)

sc-424246-ACT-2mGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 Lentiviral Activation Particles (m)

sc-424246-LACmGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 Lentiviral Activation Particles (m2)

sc-424246-LAC-2mGene ActivationPuro, Blast, Hygro0
(0)

ZO-3 siRNA, shRNA Plasmid and shRNA Lentiviral Particle Gene Silencers

Empty Table HeaderProduct NameCATALOG #SpeciesAPPLICATIONSMARKERCitationsRATING

ZO-3 siRNA (h)

sc-43538hGene SilencingN/A
1
(0)

ZO-3 shRNA Plasmid (h)

sc-43538-SHhGene SilencingPuromycin
1
(0)

ZO-3 shRNA (h) Lentiviral Particles

sc-43538-VhGene SilencingPuromycin
1
(0)

ZO-3 siRNA (m)

sc-43539mGene SilencingN/A0
(0)

ZO-3 shRNA Plasmid (m)

sc-43539-SHmGene SilencingPuromycin0
(0)

ZO-3 shRNA (m) Lentiviral Particles

sc-43539-VmGene SilencingPuromycin0
(0)