ZNF74 Inhibitors
The core of ZNF74 inhibitors leans heavily on the disruption of zinc ion availability or the interference with zinc-dependent processes. In zinc finger proteins, the zinc ion plays a pivotal role in maintaining the structural integrity of the protein. Removing or sequestering this ion can disrupt the protein's function.
Additionally, certain compounds, such as Quercetin and 8-hydroxyquinoline, while not specific to zinc, can modulate zinc-dependent processes, thereby influencing the activity of zinc finger proteins. The primary approach in targeting ZNF74 hinges on manipulating its zinc-dependent nature, either through direct interaction with the protein or altering zinc bioavailability.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
TPEN | 16858-02-9 | sc-200131 | 100 mg | $127.00 | 10 | |
A metal chelator that can remove zinc ions, potentially affecting the functionality of zinc finger proteins like ZNF74. | ||||||
Zinpyr-1 | 288574-78-7 | sc-213182 | 5 mg | $215.00 | 50 | |
A fluorescent sensor for zinc that can also sequester zinc, possibly impacting ZNF74. | ||||||
5-Sulfosalicylic acid dihydrate | 5965-83-3 | sc-202892 sc-202892A | 100 g 500 g | $53.00 $81.00 | 2 | |
It binds to zinc and could influence the zinc-finger functionality of ZNF74. | ||||||
1,10-Phenanthroline | 66-71-7 | sc-255888 sc-255888A | 2.5 g 5 g | $23.00 $31.00 | ||
A chelator known to bind zinc, potentially altering the structure or function of ZNF74. | ||||||
Deferoxamine | 70-51-9 | sc-507390 | 5 mg | $250.00 | ||
Though primarily an iron chelator, it can influence metal homeostasis, which might affect ZNF74 indirectly. | ||||||
Disulfiram | 97-77-8 | sc-205654 sc-205654A | 50 g 100 g | $52.00 $87.00 | 7 | |
While primarily used as an alcohol deterrent, it can bind metals and potentially influence zinc-dependent proteins like ZNF74. | ||||||