Date published: 2026-3-17

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1,10-Phenanthroline (CAS 66-71-7)

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Application:
1,10-Phenanthroline is a ligand employed in the spectrophotometric determination of metals and photocatalytic reduction of carbon dioxide
CAS Number:
66-71-7
Purity:
≥99%
Molecular Weight:
180.21
Molecular Formula:
C12H8N2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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1,10-Phenanthroline is a versatile ligand employed in the spectrophotometric determination of metals and photocatalytic reduction of carbon dioxide. Building block for metallomacrocycles. Ligand used in a mild, copper (II)-catalyzed cross-coupling of organoboronic acids and sulfinate salts leading to aryl- and alkenylsulfones.


1,10-Phenanthroline (CAS 66-71-7) References

  1. In vitro activity of N-phenyl-1,10-phenanthroline-2-amines against tachyzoites and bradyzoites of Toxoplasma gondii.  |  Martins-Duarte, ES., et al. 2021. Bioorg Med Chem. 50: 116467. PMID: 34666274
  2. Preparation, cytotoxic activity and DNA interaction studies of new platinum(II) complexes with 1,10-phenanthroline and 5-alkyl-1,3,4-oxadiazol-2(3H)-thione derivatives.  |  Souza, WA., et al. 2022. J Inorg Biochem. 237: 111993. PMID: 36108344
  3. Novel cytotoxic 1,10-phenanthroline-triterpenoid amphiphiles with supramolecular characteristics capable of coordinating 64Cu(II) labels.  |  Bildziukevich, U., et al. 2022. Org Biomol Chem. 20: 8157-8163. PMID: 36222062
  4. Design, synthesis, molecular modeling, and bioactivity evaluation of 1,10-phenanthroline and prodigiosin (Ps) derivatives and their Copper(I) complexes against mTOR and HDAC enzymes as highly potent and effective new anticancer therapeutic drugs.  |  Cetin, MM., et al. 2022. Front Pharmacol. 13: 980479. PMID: 36267272
  5. Optimization of Castor Oil-Based Ion Selective Electrode (ISE) with Active Agent 1,10-Phenanthroline for Aqueous Pb2+ Analysis.  |  Nisah, K., et al. 2022. Membranes (Basel). 12: PMID: 36295746
  6. Dual-Ligand Strategy Employing Rigid 2,5-Thiophenedicarboxylate and 1,10-Phenanthroline as Coligands for Solvothermal Synthesis of Eight Lanthanide(III) Coordination Polymers: Structural Diversity, DFT Study, and Exploration of the Luminescent Tb(III) Coordination Polymer as an Efficient Chemical Sensor for Nitroaromatic Compounds.  |  Ashashi, NA., et al. 2022. ACS Omega. 7: 41370-41391. PMID: 36406551
  7. Antimicrobial Resistance Challenged with Platinum(II) and Palladium(II) Complexes Containing 1,10-Phenanthroline and 5-Amino-1,3,4-Thiadiazole-2(3H)-Thione in Campylobacter jejuni.  |  Lacerda, ML., et al. 2022. Antibiotics (Basel). 11: PMID: 36421289
  8. Transition-Metal-Free Intermolecular Hydrocarbonation of Styrenes Mediated by NaH/1,10-Phenanthroline.  |  Nozawa-Kumada, K., et al. 2023. Chemistry. 29: e202203143. PMID: 36599804
  9. [AuIII(N^N)Br2](PF6): A Class of Antibacterial and Antibiofilm Complexes (N^N = 2,2'-Bipyridine and 1,10-Phenanthroline Derivatives).  |  Aragoni, MC., et al. 2023. Inorg Chem. 62: 2924-2933. PMID: 36728360
  10. Poly(3-amino-carbazole) derivatives containing 1,10-phenanthroline and 8-hydroxyquinoline ligands: Synthesis, properties and application as ion sensors.  |  Zhang, D., et al. 2023. Spectrochim Acta A Mol Biomol Spectrosc. 295: 122608. PMID: 36947941
  11. Zinc trafficking: 1,10-phenanthroline, glutathione, and other metal binding ligands form adducts with proteomic Zn2.  |  Fatema, K., et al. 2023. Metallomics. 15: PMID: 37086095
  12. A comprehensive assessment of carbon steel corrosion inhibition by 1,10-phenanthroline in the acidic environment: insights from experimental and computational studies.  |  Belhadi, M., et al. 2023. Environ Sci Pollut Res Int.. PMID: 37195616
  13. First 24-Membered Macrocyclic 1,10-Phenanthroline-2,9-Diamides-An Efficient Switch from Acidic to Alkaline Extraction of f-Elements.  |  Lemport, PS., et al. 2023. Int J Mol Sci. 24: PMID: 37373410

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

1,10-Phenanthroline, 2.5 g

sc-255888
2.5 g
$23.00

1,10-Phenanthroline, 5 g

sc-255888A
5 g
$32.00