ZNF74 Activators encompasses a group of compounds designed to influence the activity of the ZNF74 protein, primarily by modulating its dependence on zinc ions for structural stability and function. These activators include zinc ion-inducing compounds and molecules that affect cellular pathways related to zinc homeostasis and signaling. DTPA function as zinc chelators, binding to zinc ions and reducing their availability within the cellular environment. By doing so, these chelators disrupt the essential zinc-dependent structural motifs of ZNF74, leading to its inactivation.
Additionally, Clioquinol is a metal-binding compound that chelates zinc ions, further diminishing the pool of free zinc ions in the cell and interfering with the zinc-dependent function of proteins like ZNF74. Quercetin and 8-Hydroxyquinoline indirectly influence zinc-dependent processes by impacting cellular pathways involved in zinc homeostasis and zinc-dependent signaling. This disruption can indirectly affect the activity of zinc finger proteins like ZNF74.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Diethylenetriaminepentaacetic acid | 67-43-6 | sc-214890 sc-214890A | 5 g 50 g | $75.00 $234.00 | 1 | |
DTPA is a zinc chelating agent that can bind to zinc ions, similar to TPEN, reducing zinc availability in the cell and potentially impacting the function of zinc finger proteins, including ZNF74. | ||||||
Clioquinol | 130-26-7 | sc-201066 sc-201066A | 1 g 5 g | $45.00 $115.00 | 2 | |
Clioquinol is a metal-binding compound that chelates zinc ions, decreasing the pool of free zinc ions in the cell. This reduction in zinc availability can interfere with the zinc-dependent function of proteins like ZNF74. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid, can indirectly influence zinc-dependent processes by affecting cellular pathways involved in zinc homeostasis or signaling. This may impact the activity of zinc finger proteins like ZNF74. | ||||||