ZNF71 inhibitors represent a specialized class of chemical compounds designed to target and modulate the activity of the ZNF71 protein within biological systems. ZNF71, also known as Zinc Finger Protein 71, is a member of the zinc finger transcription factor family, characterized by the presence of zinc finger motifs that enable binding to specific DNA sequences. ZNF71 plays a critical role in the regulation of gene expression by acting as a transcription factor that can activate or repress the transcription of target genes. Inhibitors of ZNF71 are designed to interact with this protein, either by directly binding to it or by disrupting its DNA-binding capabilities, with the aim of modulating specific cellular processes associated with gene expression and transcriptional regulation.
The development and study of ZNF71 inhibitors are driven by the increasing recognition of ZNF71's importance in controlling the transcriptional landscape of cells. By modulating the activity of ZNF71, these inhibitors provide a valuable tool for researchers to investigate the molecular mechanisms underlying gene regulation and transcriptional control in various biological contexts. ZNF71 may influence processes such as cell differentiation, development, and response to environmental cues, making it a pivotal player in cellular homeostasis. Researchers in this field are continuously exploring novel chemical compounds and strategies to fine-tune ZNF71 inhibition, aiming to gain insights into the intricate genetic networks that drive cellular responses. Understanding the role of ZNF71 inhibitors can provide valuable contributions to the broader field of molecular biology, elucidating the complexities of transcriptional regulation and gene expression control in diverse biological systems.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
DRB | 53-85-0 | sc-200581 sc-200581A sc-200581B sc-200581C | 10 mg 50 mg 100 mg 250 mg | $43.00 $189.00 $316.00 $663.00 | 6 | |
DRB inhibits RNA polymerase II, which can hinder the transcription of many genes, potentially including ZNF71. | ||||||
Flavopiridol Hydrochloride | 131740-09-5 | sc-207687 | 10 mg | $317.00 | ||
Flavopiridol is a CDK inhibitor, which can impact the cell cycle and transcriptional regulation, potentially affecting ZNF71 expression. | ||||||
17-AAG | 75747-14-7 | sc-200641 sc-200641A | 1 mg 5 mg | $67.00 $156.00 | 16 | |
This compound inhibits HSP90, a chaperone protein. If ZNF71 interacts with HSP90 for proper folding, 17-AAG could affect its function. | ||||||
Triptolide | 38748-32-2 | sc-200122 sc-200122A | 1 mg 5 mg | $90.00 $204.00 | 13 | |
Triptolide inhibits the transcriptional activity of several transcription factors, which might influence ZNF71 expression or activity. | ||||||
I-BET 151 Hydrochloride | 1300031-49-5 (non HCl Salt) | sc-391115 | 10 mg | $450.00 | 2 | |
This compound inhibits BET bromodomains, which play roles in transcriptional regulation. It might have effects on ZNF71 transcription. | ||||||
C646 | 328968-36-1 | sc-364452 sc-364452A | 10 mg 50 mg | $265.00 $944.00 | 5 | |
C646 is a p300/CBP inhibitor. Given that p300/CBP are coactivators in many transcriptional processes, ZNF71 activity might be affected. | ||||||
UNC0638 | 1255580-76-7 | sc-397012 | 10 mg | $315.00 | ||
UNC0638 inhibits G9a and GLP methyltransferase activity, potentially affecting chromatin state and ZNF71 expression. | ||||||
EPZ6438 | 1403254-99-8 | sc-507456 | 1 mg | $66.00 | ||
An inhibitor of EZH2, a component of the PRC2 complex involved in gene repression, which could influence ZNF71 expression. | ||||||
3-Deazaneplanocin, HCl salt | 120964-45-6 | sc-351856 sc-351856A sc-351856B | 1 mg 5 mg 10 mg | $256.00 $612.00 $936.00 | 2 | |
DZNep depletes EZH2 levels and might have broad effects on gene expression, including ZNF71. | ||||||
Chaetocin | 28097-03-2 | sc-200893 | 200 µg | $126.00 | 5 | |
Inhibits SUV39H1, a histone methyltransferase, potentially altering chromatin structure and ZNF71 expression. | ||||||