Date published: 2026-4-1

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ZNF425 Inhibitors

ZNF425 inhibitors constitute a distinct category of chemical compounds engineered to target and modulate the activity of ZNF425, also known as Zinc Finger Protein 425. ZNF425 is a transcription factor, and transcription factors play a pivotal role in regulating gene expression within cells. These proteins orchestrate the intricate process of gene activation or repression, thereby influencing a wide array of cellular functions. ZNF425, specifically, contains zinc finger domains, known for their capacity to interact with specific DNA sequences, which allows the protein to bind to and regulate the transcription of specific genes. While the precise functions of ZNF425 are still being elucidated, it has been implicated in various cellular processes, including cell differentiation, development, and response to environmental cues. Inhibitors targeting ZNF425 are designed to interact with this specific protein, potentially influencing its DNA-binding capabilities, interactions with co-regulatory proteins, or participation in cellular processes where ZNF425 is involved.

Structurally, ZNF425 inhibitors are meticulously crafted to engage specific regions or binding sites on the ZNF425 protein. This interaction can hinder the normal functioning of ZNF425 as a transcription factor, potentially leading to changes in gene expression patterns and subsequent cellular responses. The mechanisms through which ZNF425 inhibitors exert their effects can vary, but their fundamental purpose is to provide researchers with a valuable tool for exploring the roles of ZNF425 in various biological contexts. Investigating the biochemical and functional aspects of ZNF425 and its modulation by inhibitors can contribute to a deeper understanding of gene regulation, cellular development, and signaling pathways, ultimately advancing our knowledge of fundamental molecular and cellular processes in biology.

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

5-Azacytidine

320-67-2sc-221003
500 mg
$280.00
4
(1)

This compound is a DNA methyltransferase inhibitor and could inhibit the methylation-mediated expression of genes.

Trichostatin A

58880-19-6sc-3511
sc-3511A
sc-3511B
sc-3511C
sc-3511D
1 mg
5 mg
10 mg
25 mg
50 mg
$152.00
$479.00
$632.00
$1223.00
$2132.00
33
(3)

A histone deacetylase inhibitor that can affect chromatin structure and gene expression.

Actinomycin D

50-76-0sc-200906
sc-200906A
sc-200906B
sc-200906C
sc-200906D
5 mg
25 mg
100 mg
1 g
10 g
$74.00
$243.00
$731.00
$2572.00
$21848.00
53
(3)

Binds to DNA and inhibits RNA synthesis, thereby preventing gene transcription.

α-Amanitin

23109-05-9sc-202440
sc-202440A
1 mg
5 mg
$269.00
$1050.00
26
(2)

Inhibits RNA polymerase II, potentially downregulating gene transcription.

Mithramycin A

18378-89-7sc-200909
1 mg
$55.00
6
(1)

Binds to DNA and inhibits transcription, especially of genes with GC-rich promoters.

DRB

53-85-0sc-200581
sc-200581A
sc-200581B
sc-200581C
10 mg
50 mg
100 mg
250 mg
$43.00
$189.00
$316.00
$663.00
6
(1)

Inhibits RNA polymerase II elongation.

Pladienolide B

445493-23-2sc-391691
sc-391691B
sc-391691A
sc-391691C
sc-391691D
sc-391691E
0.5 mg
10 mg
20 mg
50 mg
100 mg
5 mg
$299.00
$5699.00
$11099.00
$25500.00
$66300.00
$2875.00
63
(2)

Targets the SF3b complex, affecting spliceosome function and mRNA processing.

(±)-JQ1

1268524-69-1sc-472932
sc-472932A
5 mg
25 mg
$231.00
$863.00
1
(0)

Inhibits bromodomain-containing proteins, affecting gene transcription.

Spliceostatin A

391611-36-2sc-507481
1 mg
$1800.00
(0)

Binds to SF3b and inhibits spliceosome function, affecting mRNA processing.