Date published: 2026-3-31

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ZNF414 Inhibitors

ZNF414 Inhibitors are a specialized class of chemical compounds designed to selectively target and inhibit the function of the zinc finger protein 414 (ZNF414). ZNF414 is part of a larger family of C2H2-type zinc finger proteins, which are characterized by their ability to bind DNA through zinc-coordinated finger-like motifs. These proteins play critical roles in the regulation of gene expression by binding to specific DNA sequences and influencing the transcription of various genes. ZNF414, in particular, is involved in the modulation of transcriptional networks that govern a variety of cellular processes, including cell cycle progression, differentiation, and response to environmental changes. The inhibition of ZNF414 allows researchers to study its specific role in these processes, providing a deeper understanding of the molecular mechanisms that regulate gene expression. In scientific research, ZNF414 Inhibitors serve as valuable tools for probing the functions and interactions of ZNF414 within the cell. By selectively inhibiting ZNF414, researchers can dissect the complex regulatory networks in which this protein is involved, identifying the genes it directly regulates and the downstream effects of its inhibition. This is particularly important in studies aimed at understanding how alterations in transcription factor activity can lead to changes in cellular behavior. Additionally, ZNF414 Inhibitors can be used to explore the broader implications of zinc finger protein function in cellular homeostasis and development. Through the use of these inhibitors, scientists gain insights into the fundamental processes that control gene expression and how these processes are altered in different cellular contexts. The study of ZNF414 and its inhibitors contributes to the broader field of gene regulation, shedding light on the intricate balance of transcriptional control that is essential for normal cellular function.

Items 1 to 10 of 11 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Staurosporine

62996-74-1sc-3510
sc-3510A
sc-3510B
100 µg
1 mg
5 mg
$82.00
$153.00
$396.00
113
(4)

Inhibits a broad range of kinases that could phosphorylate ZNF414, thereby inhibiting its kinase-dependent activity.

Bortezomib

179324-69-7sc-217785
sc-217785A
2.5 mg
25 mg
$135.00
$1085.00
115
(2)

Targets proteasomal degradation pathways, which could degrade misfolded or damaged ZNF414, inhibiting its function.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Inhibits mTOR, which could be necessary for ZNF414 function, especially if ZNF414 is involved in growth control.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

Inhibits PI3K, possibly reducing ZNF414 activity by disrupting PI3K/Akt signaling pathways ZNF414 may be part of.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

Inhibits MEK, which could decrease ERK pathway activity, potentially inhibiting downstream ZNF414 activity.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

Inhibits MEK and could reduce ERK pathway signaling, potentially resulting in inhibition of ZNF414 activity.

SP600125

129-56-6sc-200635
sc-200635A
10 mg
50 mg
$40.00
$150.00
257
(3)

Inhibits JNK, potentially reducing activity of ZNF414 if it is regulated by JNK signaling pathways.

SB 203580

152121-47-6sc-3533
sc-3533A
1 mg
5 mg
$90.00
$349.00
284
(5)

Inhibits p38 MAP kinase, potentially inhibiting ZNF414 activity if it is downstream of p38 MAPK signaling.

Wortmannin

19545-26-7sc-3505
sc-3505A
sc-3505B
1 mg
5 mg
20 mg
$67.00
$223.00
$425.00
97
(3)

Inhibits PI3K, potentially disrupting PI3K/Akt signaling and subsequent ZNF414 activity if connected.

Dasatinib

302962-49-8sc-358114
sc-358114A
25 mg
1 g
$70.00
$145.00
51
(1)

Inhibits Src family tyrosine kinases, which could inhibit ZNF414 activity by blocking necessary phosphorylation.