ZNF281 Activators
ZNF281 activators are diverse in their chemical structure and function. They belong to different classes of compounds, including polyphenols (Curcumin, Resveratrol, Quercetin), inorganics (LiCl), synthetic small molecules (BIO, Chir99021, SRT1720, SRT2104), carboxylic acids (Valproic Acid), ketones (Trichostatin A), isothiocyanates (Sulforaphane), and esters (Dimethyl Fumarate).These compounds can have distinct mechanisms of action, but they all indirectly affect ZNF281 through the modulation of different cellular pathways.
For instance, Curcumin, LiCl, BIO, and Chir99021 can activate the Wnt/β-catenin pathway, which ZNF281 is known to be involved in. Valproic Acid and Trichostatin A modulate chromatin structure by inhibiting HDAC, which can alter ZNF281 expression. Resveratrol, Quercetin, SRT1720, and SRT2104 can activate the SIRT1 pathway, which can influence the Wnt/β-catenin pathway and, in turn, ZNF281. Lastly, Sulforaphane and Dimethyl Fumarate can activate the Nrf2 pathway, thereby influencing ZNF281 through the cellular oxidative stress response.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin can activate the Wnt/β-catenin pathway, which ZNF281 is involved in, thereby potentially increasing ZNF281 activity. | ||||||
Lithium | 7439-93-2 | sc-252954 | 50 g | $214.00 | ||
Lithium chloride can activate the Wnt/β-catenin pathway, indirectly influencing ZNF281. | ||||||
GSK-3 Inhibitor IX | 667463-62-9 | sc-202634 sc-202634A sc-202634B | 1 mg 10 mg 50 mg | $58.00 $188.00 $884.00 | 10 | |
BIO (GSK-3 Inhibitor IX) is a potent and selective GSK3 inhibitor, which can activate Wnt/β-catenin pathway and thus ZNF281. | ||||||
GSK-3 Inhibitor XVI | 252917-06-9 | sc-221691 sc-221691A | 5 mg 25 mg | $180.00 $610.00 | 4 | |
Chir99021(GSK-3 Inhibitor XVI) is a potent GSK-3 inhibitor, which can activate the Wnt/β-catenin pathway, potentially influencing ZNF281. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic Acid is a histone deacetylase (HDAC) inhibitor, which may alter ZNF281 expression by modifying chromatin structure. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is an HDAC inhibitor, which can modulate ZNF281 expression by changing chromatin structure. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol can activate the SIRT1 pathway, which is known to influence the Wnt/β-catenin pathway and indirectly ZNF281. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin can activate the SIRT1 pathway, which can influence the Wnt/β-catenin pathway and indirectly ZNF281. | ||||||
SRT1720 | 1001645-58-4 | sc-364624 sc-364624A | 5 mg 10 mg | $197.00 $364.00 | 13 | |
SRT1720 is a specific SIRT1 activator, which can influence the Wnt/β-catenin pathway, indirectly affecting ZNF281. | ||||||
Dimethyl fumarate | 624-49-7 | sc-239774 | 25 g | $28.00 | 6 | |
Dimethyl Fumarate can activate the Nrf2 pathway, indirectly influencing ZNF281 through cellular oxidative stress response. | ||||||