Zic1 Activators
Zic1 activators belong to a distinct chemical class known for their ability to modulate the expression and function of the Zic1 transcription factor. Zic1, a member of the Zinc-finger of the cerebellum (Zic) family of transcription factors, plays a crucial role in embryonic development, particularly in the formation of various tissues and organs. The Zic1 gene is highly conserved across species and is essential for the regulation of numerous downstream target genes involved in various developmental processes. Zic1 activators are chemical compounds or molecules that have been identified and studied for their capacity to enhance the transcriptional activity of Zic1.
Chemically, Zic1 activators can encompass a diverse range of small molecules, peptides, or organic compounds that interact with Zic1 or its regulatory elements to enhance its activity as a transcription factor. These activators may function through various mechanisms, such as promoting Zic1's binding to DNA, stabilizing its protein structure, or modulating its interactions with co-factors. By specifically targeting Zic1, these compounds have the potential to influence the precise timing and expression levels of Zic1 target genes, which are critical for embryonic development and tissue differentiation.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Retinoic Acid, all trans | 302-79-4 | sc-200898 sc-200898A sc-200898B sc-200898C | 500 mg 5 g 10 g 100 g | $66.00 $325.00 $587.00 $1018.00 | 28 | |
Retinoic acid can directly activate gene expression related to developmental processes and indirectly activates the expression of transcription factors like Zic1. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Forskolin can activate adenylate cyclase, leading to increased cAMP levels which can influence various transcription factors including indirectly activates Zic1. | ||||||
Valproic Acid | 99-66-1 | sc-213144 | 10 g | $87.00 | 9 | |
Valproic acid is an HDAC inhibitor, indirectly activates leading to changes in chromatin structure and influencing transcription factors like Zic1. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
Trichostatin A is another HDAC inhibitor, which can influence chromatin structure and indirectly activates the expression of Zic1. | ||||||