ZFAT inhibitors, as a chemical class, would be constituted of molecules meticulously designed to target the ZFAT protein or its associated molecular pathways, effectively diminishing or negating its activity within cells. These compounds could achieve their inhibitory effects by multiple means: they might bind directly to the ZFAT protein, impeding its interaction with other cellular components, or they could act on the upstream or downstream pathways that control its expression or functionality. The precision of these inhibitors would be of paramount importance, as any off-target interactions could lead to unforeseen cellular consequences. Advanced techniques in the realm of drug design, such as computational modeling, structure-based drug design, and high-throughput screening, would likely be employed to identify and refine molecules with potential as ZFAT inhibitors.
The iterative process of designing and developing ZFAT inhibitors would involve a series of meticulous tests both in vitro (in cell cultures) to ascertain their efficacy and specificity. A profound understanding of the biological role of ZFAT within cellular processes is pivotal, ensuring that the inhibitor does not inadvertently disrupt essential cellular functionalities.
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Actinomycin D | 50-76-0 | sc-200906 sc-200906A sc-200906B sc-200906C sc-200906D | 5 mg 25 mg 100 mg 1 g 10 g | $74.00 $243.00 $731.00 $2572.00 $21848.00 | 53 | |
Actinomycin D binds to DNA and inhibits RNA synthesis, which could prevent the transcription of the ZFAT gene. | ||||||
Cycloheximide | 66-81-9 | sc-3508B sc-3508 sc-3508A | 100 mg 1 g 5 g | $41.00 $84.00 $275.00 | 127 | |
By blocking the peptide exit tunnel on the ribosome, cycloheximide inhibits protein synthesis, possibly halting ZFAT translation. | ||||||
5-Azacytidine | 320-67-2 | sc-221003 | 500 mg | $280.00 | 4 | |
This DNA methyltransferase inhibitor can change gene expression by affecting DNA methylation patterns, potentially downregulating ZFAT. | ||||||
Trichostatin A | 58880-19-6 | sc-3511 sc-3511A sc-3511B sc-3511C sc-3511D | 1 mg 5 mg 10 mg 25 mg 50 mg | $152.00 $479.00 $632.00 $1223.00 $2132.00 | 33 | |
As a histone deacetylase inhibitor, trichostatin A can affect chromatin structure and gene expression, which might impact ZFAT transcription. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
By inhibiting mTOR, a key protein in protein synthesis regulation, rapamycin can reduce overall protein translation, affecting ZFAT indirectly. | ||||||
Wortmannin | 19545-26-7 | sc-3505 sc-3505A sc-3505B | 1 mg 5 mg 20 mg | $67.00 $223.00 $425.00 | 97 | |
Another inhibitor of PI3K, wortmannin might indirectly influence ZFAT expression. | ||||||