Date published: 2026-2-14

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XKR9 Activators

XKR9, also known as XK-related protein 9, is a member of the XK family of proteins, which are characterized by the presence of a conserved sequence motif known as the XK domain. XKR9 is encoded by the XKR9 gene located on human chromosome 8. The XK family members are type II membrane proteins, which means they have a single transmembrane domain with their N-terminus located in the cytoplasm and the C-terminus in the extracellular space.While the precise function of XKR9 has not been extensively characterized, proteins in this family are often involved in various cellular processes, including apoptosis, cell signaling, and transport across the membrane. The XK domain suggests that XKR9 may play a role in transmembrane transport or in maintaining membrane integrity and structure.

The expression pattern of XKR9 may provide clues to its function, and it is often studied in conjunction with other XK family members to understand any potential redundancy or specialization of function. Additionally, the localization of XKR9 within the cell, its expression levels in different tissues, and its regulation can offer insights into the physiological contexts where it plays a critical role.Research into XKR9 may also investigate its potential interactions with other proteins, which can elucidate pathways and processes it may influence. For example, if XKR9 interacts with proteins involved in cell adhesion, it might imply a role in cell-cell interactions or migration.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin is an activator of adenylyl cyclase, potentially affecting cAMP levels which could indirectly influence XKR9 activity if XKR9 is cAMP-responsive.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Ionomycin is a calcium ionophore, raising intracellular calcium levels, which might impact XKR9 if it is sensitive to calcium signaling.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C (PKC), which could indirectly affect XKR9 if it is part of or regulated by PKC-mediated signaling pathways.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin activates the PI3K/Akt signaling pathway, which might intersect with XKR9's function if it is involved in metabolic regulation.

Bis(pinacolato)diboron

73183-34-3sc-252467
sc-252467A
1 g
5 g
$44.00
$82.00
(0)

PDGF activates the PDGFR signaling pathway, potentially influencing XKR9 if it is connected to this pathway.

Lysophosphatidic Acid

325465-93-8sc-201053
sc-201053A
5 mg
25 mg
$98.00
$341.00
50
(3)

LPA activates G-protein coupled receptors (GPCRs), potentially influencing XKR9 if it is connected to GPCR-mediated signaling.