Date published: 2026-4-1

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XKR7 Activators

XKR7, also known as XK-related protein 7, is a transmembrane protein that belongs to the XK family. The protein is encoded by the XKR7 gene which resides on human chromosome 1. Members of the XK family, including XKR7, share a characteristic feature, the XK domain, which is thought to play a role in various cellular functions, although the specific role of XKR7 is not fully understood.As a transmembrane protein, XKR7 has a structural orientation that spans the lipid bilayer of cell membranes with termini on both the intracellular and extracellular sides. This positioning allows it to potentially participate in intracellular signaling, cell-to-cell communication, or transport processes across the cell membrane.

The expression of XKR7 varies among different tissue types and developmental stages, suggesting that it may have distinct physiological roles depending on its context. The exact function of XKR7 remains an active area of research, but it may be involved in processes such as cell adhesion, apoptosis, or the regulation of membrane potential and ion homeostasis.Studying the interaction partners of XKR7 could provide additional insight into its function. For instance, if XKR7 were found to interact with proteins related to cell junctions, it might indicate a role in maintaining cellular integrity or facilitating communication between neighboring cells.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$78.00
$153.00
$740.00
$1413.00
$2091.00
73
(3)

Forskolin activates adenylyl cyclase, increasing cAMP levels, which could indirectly influence XKR7 if it is responsive to cAMP-mediated signaling.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$78.00
$270.00
80
(4)

Ionomycin is a calcium ionophore that elevates intracellular calcium, potentially impacting XKR7 if it is sensitive to calcium signaling.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$41.00
$132.00
$214.00
$500.00
$948.00
119
(6)

PMA activates protein kinase C (PKC), potentially affecting XKR7 through PKC-mediated signaling pathways.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$156.00
$1248.00
$12508.00
82
(1)

Insulin triggers the PI3K/Akt pathway, which might influence XKR7 if it plays a role in metabolic or growth signaling.

Bis(pinacolato)diboron

73183-34-3sc-252467
sc-252467A
1 g
5 g
$44.00
$82.00
(0)

PDGF activates the PDGFR pathway, potentially affecting XKR7 if it is linked to PDGFR signaling.

Lysophosphatidic Acid

325465-93-8sc-201053
sc-201053A
5 mg
25 mg
$98.00
$341.00
50
(3)

LPA activates GPCRs, potentially influencing XKR7 through GPCR-mediated signaling.