Date published: 2025-11-25

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XKR6 Activators

XKR6, or XK-related protein 6, is part of the XK family of proteins, characterized by the presence of the XK domain. This family is known for its role in various cellular processes, although the precise function of XKR6 remains to be fully elucidated. The XKR6 protein is encoded by the XKR6 gene, which is located on human chromosome 8.As a member of the XK family, XKR6 is a transmembrane protein that straddles the lipid bilayer of cell membranes. This structural feature positions XKR6 to potentially engage in activities such as signal transduction, cell adhesion, and the transport of molecules across the cell membrane. The transmembrane domains are critical for the protein's anchoring and function within the cellular architecture.

XKR6 expression is tissue-specific and may vary throughout different developmental stages, suggesting it plays diverse roles in various biological contexts. The protein's functions might include involvement in apoptosis, cell communication, and the maintenance of cell membrane integrity and ion homeostasis.The study of XKR6's interaction partners and downstream signaling pathways is valuable for understanding its biological roles. If XKR6 is found to interact with proteins involved in intercellular junctions, it could indicate a function related to cell-to-cell interactions or barrier formation.Mutations or dysregulation of the XKR6 gene may have associations with certain pathological conditions, which makes it a protein of interest in biomedical research. As research progresses, the understanding of XKR6's mechanisms of action and its role in health and disease may lead to novel insights in cellular biology and possible applications. The exploration of XKR6's function is thus an area of scientific inquiry that holds promise for future discoveries in cell biology and medicine.

SEE ALSO...

Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Forskolin

66575-29-9sc-3562
sc-3562A
sc-3562B
sc-3562C
sc-3562D
5 mg
50 mg
1 g
2 g
5 g
$76.00
$150.00
$725.00
$1385.00
$2050.00
73
(3)

Forskolin activates adenylyl cyclase, potentially influencing XKR6 activity through increased cAMP levels, if XKR6 is cAMP-responsive.

Ionomycin

56092-82-1sc-3592
sc-3592A
1 mg
5 mg
$76.00
$265.00
80
(4)

Ionomycin is a calcium ionophore that raises intracellular calcium levels, which might affect XKR6 if it is sensitive to calcium signaling.

PMA

16561-29-8sc-3576
sc-3576A
sc-3576B
sc-3576C
sc-3576D
1 mg
5 mg
10 mg
25 mg
100 mg
$40.00
$129.00
$210.00
$490.00
$929.00
119
(6)

PMA activates protein kinase C (PKC), potentially affecting XKR6 if it is part of or regulated by PKC-mediated signaling pathways.

Insulin

11061-68-0sc-29062
sc-29062A
sc-29062B
100 mg
1 g
10 g
$153.00
$1224.00
$12239.00
82
(1)

Insulin activates the PI3K/Akt signaling pathway, which might intersect with XKR6's function if it is involved in metabolic regulation.

Bis(pinacolato)diboron

73183-34-3sc-252467
sc-252467A
1 g
5 g
$43.00
$80.00
(0)

PDGF activates the PDGFR signaling pathway, potentially influencing XKR6 if it is connected to this pathway.

Lysophosphatidic Acid

325465-93-8sc-201053
sc-201053A
5 mg
25 mg
$96.00
$334.00
50
(3)

LPA activates G-protein coupled receptors (GPCRs), potentially influencing XKR6 if it is connected to GPCR-mediated signaling.