Date published: 2026-5-15

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WDR65 Activators

WDR65 Activators constitute a class of chemical compounds recognized for their capability to modulate the activity of the WDR65 gene. WDR65, also known as WD Repeat Domain 65, is a gene that encodes a protein whose functions are still being explored within the realm of molecular biology. Activators of WDR65 are molecules that possess the capacity to either enhance the expression of the WDR65 gene or augment its biological activity within a cell. These compounds serve as valuable tools for researchers aiming to decipher the biological significance of WDR65 and its potential involvement in various cellular processes.

The specific mechanisms by which WDR65 activators exert their effects are currently a subject of active scientific investigation. These molecules may act at the transcriptional or post-transcriptional level, potentially influencing the production of WDR65 protein or modifying its interactions with other cellular components. By manipulating WDR65 activity, researchers aim to unravel its biological functions, which may include roles in cellular signaling, molecular pathways, or cellular responses to internal or external stimuli. Exploring WDR65 activators offers the promise of shedding light on the molecular pathways and cellular processes governed by this gene, thereby advancing our understanding of its significance in normal cellular physiology and potentially leading to novel insights in fields such as molecular biology and genetics.

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Items 1 to 10 of 12 total

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Product NameCAS #Catalog #QUANTITYPriceCitationsRATING

Dexamethasone

50-02-2sc-29059
sc-29059B
sc-29059A
100 mg
1 g
5 g
$91.00
$139.00
$374.00
36
(1)

Dexamethasone, a glucocorticoid receptor agonist, can regulate gene expression which may lead to changes in the expression levels of genes such as WDR65.

Spironolactone

52-01-7sc-204294
50 mg
$109.00
3
(1)

Spironolactone, an antagonist of the aldosterone receptor, may alter gene expression profiles that could include modulation of WDR65 expression.

Valproic Acid

99-66-1sc-213144
10 g
$87.00
9
(1)

Valproic acid, a histone deacetylase inhibitor, can affect chromatin remodeling and potentially influence the expression of various genes including WDR65.

AICAR

2627-69-2sc-200659
sc-200659A
sc-200659B
50 mg
250 mg
1 g
$65.00
$280.00
$400.00
48
(2)

AICAR is an activator of AMP-activated protein kinase (AMPK) that can lead to transcriptional changes, possibly affecting WDR65 expression.

U-0126

109511-58-2sc-222395
sc-222395A
1 mg
5 mg
$64.00
$246.00
136
(2)

U0126 is an inhibitor of MEK, which could indirectly modulate gene expression patterns, potentially impacting WDR65 levels.

Rapamycin

53123-88-9sc-3504
sc-3504A
sc-3504B
1 mg
5 mg
25 mg
$63.00
$158.00
$326.00
233
(4)

Rapamycin inhibits mTOR signaling, which may result in a broad change in gene expression that could hypothetically upregulate WDR65.

SB 431542

301836-41-9sc-204265
sc-204265A
sc-204265B
1 mg
10 mg
25 mg
$82.00
$216.00
$416.00
48
(1)

SB431542 is an inhibitor of the TGF-β receptor, potentially leading to altered gene expression that may include WDR65 upregulation.

LY 294002

154447-36-6sc-201426
sc-201426A
5 mg
25 mg
$123.00
$400.00
148
(1)

LY294002 is a PI3K inhibitor which could affect downstream signaling pathways, possibly influencing the expression of WDR65.

PD 98059

167869-21-8sc-3532
sc-3532A
1 mg
5 mg
$40.00
$92.00
212
(2)

PD98059 is a MEK inhibitor that may alter signaling pathways, leading to changes in gene expression potentially affecting WDR65.

Geldanamycin

30562-34-6sc-200617B
sc-200617C
sc-200617
sc-200617A
100 µg
500 µg
1 mg
5 mg
$39.00
$59.00
$104.00
$206.00
8
(1)

Geldanamycin binds to Hsp90, which may affect the stability and function of client proteins, potentially altering WDR65 expression.