Compounds such as Paclitaxel and Nocodazole, which modulate microtubule dynamics, can influence WDR47's role in microtubule organization and cellular transport. These agents could impact the way WDR47 interacts with microtubule structures, thereby affecting processes like intracellular trafficking and cell shape maintenance.
Actin dynamics are also crucial for WDR47's function, and compounds like Cytochalasin D, Latrunculin A, and Wiskostatin, by disrupting or stabilizing actin filaments, provide insights into WDR47's involvement in actin-mediated cellular processes. Inhibition of Cdc42 GTPase by ML141 and ROCK by Y-27632 further underscores the role of WDR47 in cytoskeletal regulation pathways. Furthermore, agents like Brefeldin A and Rapamycin, known for their roles in modulating intracellular transport and mTOR signaling pathways, respectively, might indirectly influence WDR47's functionality in these pathways. Compounds like Blebbistatin and Colchicine offer additional perspectives on WDR47's involvement in processes governed by myosin II activity and microtubule polymerization.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Taxol | 33069-62-4 | sc-201439D sc-201439 sc-201439A sc-201439E sc-201439B sc-201439C | 1 mg 5 mg 25 mg 100 mg 250 mg 1 g | $41.00 $74.00 $221.00 $247.00 $738.00 $1220.00 | 39 | |
Stabilizes microtubules, potentially affecting WDR47's role in microtubule dynamics and cellular transport. | ||||||
Nocodazole | 31430-18-9 | sc-3518B sc-3518 sc-3518C sc-3518A | 5 mg 10 mg 25 mg 50 mg | $59.00 $85.00 $143.00 $247.00 | 38 | |
Disrupts microtubule polymerization, possibly influencing WDR47's involvement in cytoskeletal organization. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $165.00 $486.00 | 64 | |
Inhibits actin polymerization, could affect WDR47's role in actin cytoskeleton regulation. | ||||||
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $265.00 $815.00 | 36 | |
Disrupts actin filaments, potentially impacting WDR47's function in actin dynamics and cellular morphology. | ||||||
Forskolin | 66575-29-9 | sc-3562 sc-3562A sc-3562B sc-3562C sc-3562D | 5 mg 50 mg 1 g 2 g 5 g | $78.00 $153.00 $740.00 $1413.00 $2091.00 | 73 | |
Increases intracellular cAMP, potentially modulating WDR47's role in cAMP-dependent signaling pathways. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $186.00 $707.00 | 88 | |
A ROCK inhibitor, could affect WDR47's involvement in cytoskeletal dynamics through the Rho-ROCK pathway. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $137.00 $512.00 | 7 | |
A Cdc42 GTPase inhibitor, potentially influencing WDR47's role in actin organization and cell morphology. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $31.00 $53.00 $124.00 $374.00 | 25 | |
Disrupts protein transport between the endoplasmic reticulum and Golgi, possibly affecting WDR47's function in vesicular trafficking. | ||||||
Rapamycin | 53123-88-9 | sc-3504 sc-3504A sc-3504B | 1 mg 5 mg 25 mg | $63.00 $158.00 $326.00 | 233 | |
An mTOR inhibitor, could influence WDR47's role in processes related to cell growth and autophagy. | ||||||
Wiskostatin | 253449-04-6 | sc-204399 sc-204399A sc-204399B sc-204399C | 1 mg 5 mg 25 mg 50 mg | $49.00 $124.00 $441.00 $828.00 | 4 | |
Inhibits N-WASP, affecting actin polymerization, potentially impacting WDR47's role in cytoskeletal reorganization. | ||||||