WDR40A Activators
The chemical class of WDR40A activators comprises a diverse array of compounds, primarily including polyphenols, flavonoids, and terpenoids. These compounds exert their activating effects on WDR40A through various mechanisms, including modulation of signaling pathways and transcriptional regulation.
Polyphenols such as curcumin, resveratrol, and ellagic acid activate WDR40A by inhibiting histone deacetylases (HDACs) and modulating the activity of transcription factors involved in WDR40A expression. By altering chromatin structure and enhancing gene transcription associated with WDR40A, these compounds promote its activation and downstream biological effects. Additionally, flavonoids like quercetin, genistein, and luteolin also activate WDR40A by similar mechanisms, further contributing to its transcriptional activity.
Terpenoids such as ursolic acid and betulinic acid activate WDR40A indirectly by modulating signaling pathways like NF-κB and MAPK, which influence gene expression patterns and transcriptional activity associated with WDR40A. By targeting these key regulatory mechanisms, the chemical class of WDR40A activators offers a promising avenue for further exploration into the modulation of WDR40A expression and its downstream biological effects.
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| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Curcumin | 458-37-7 | sc-200509 sc-200509A sc-200509B sc-200509C sc-200509D sc-200509F sc-200509E | 1 g 5 g 25 g 100 g 250 g 1 kg 2.5 kg | $37.00 $69.00 $109.00 $218.00 $239.00 $879.00 $1968.00 | 47 | |
Curcumin, a polyphenolic compound found in turmeric, activates WDR40A by modulating various signaling pathways, including NF-κB and PI3K/Akt, leading to enhanced transcriptional activity and gene expression associated with WDR40A. | ||||||
Ursolic Acid | 77-52-1 | sc-200383 sc-200383A | 50 mg 250 mg | $56.00 $180.00 | 8 | |
Ursolic acid, a pentacyclic triterpenoid present in various plants, can activate WDR40A indirectly by modulating signaling pathways such as Wnt/β-catenin and MAPK, which influence gene expression patterns and transcriptional activity associated with WDR40A. | ||||||
Resveratrol | 501-36-0 | sc-200808 sc-200808A sc-200808B | 100 mg 500 mg 5 g | $80.00 $220.00 $460.00 | 64 | |
Resveratrol, a natural polyphenol found in grapes and red wine, activates WDR40A by inhibiting HDACs and modulating the activity of transcription factors involved in WDR40A regulation, thereby promoting changes in chromatin structure and enhancing gene expression. | ||||||
Quercetin | 117-39-5 | sc-206089 sc-206089A sc-206089E sc-206089C sc-206089D sc-206089B | 100 mg 500 mg 100 g 250 g 1 kg 25 g | $11.00 $17.00 $110.00 $250.00 $936.00 $50.00 | 33 | |
Quercetin, a flavonoid abundant in fruits and vegetables, activates WDR40A through its ability to inhibit HDACs and regulate the activity of transcription factors implicated in WDR40A expression, leading to alterations in chromatin remodeling and enhanced gene transcription. | ||||||
Genistein | 446-72-0 | sc-3515 sc-3515A sc-3515B sc-3515C sc-3515D sc-3515E sc-3515F | 100 mg 500 mg 1 g 5 g 10 g 25 g 100 g | $45.00 $164.00 $200.00 $402.00 $575.00 $981.00 $2031.00 | 46 | |
Genistein, an isoflavone found in soy products, activates WDR40A by inhibiting HDACs and modulating the activity of transcription factors involved in WDR40A regulation, thereby promoting changes in chromatin structure and enhancing gene expression associated with WDR40A. | ||||||
Kaempferol | 520-18-3 | sc-202679 sc-202679A sc-202679B | 25 mg 100 mg 1 g | $99.00 $216.00 $510.00 | 11 | |
Kaempferol, a flavonoid present in various plants, activates WDR40A by inhibiting HDACs and modulating the activity of transcription factors implicated in WDR40A expression, leading to alterations in chromatin remodeling and enhanced gene transcription associated with WDR40A. | ||||||
Betulinic Acid | 472-15-1 | sc-200132 sc-200132A | 25 mg 100 mg | $117.00 $344.00 | 3 | |
Betulinic acid, a pentacyclic triterpenoid found in many plants, activates WDR40A indirectly by modulating signaling pathways such as NF-κB and MAPK, which influence gene expression patterns and transcriptional activity associated with WDR40A. | ||||||
Luteolin | 491-70-3 | sc-203119 sc-203119A sc-203119B sc-203119C sc-203119D | 5 mg 50 mg 500 mg 5 g 500 g | $27.00 $51.00 $101.00 $153.00 $1925.00 | 40 | |
Luteolin, a flavonoid abundant in fruits and vegetables, activates WDR40A through its ability to inhibit HDACs and regulate the activity of transcription factors implicated in WDR40A expression, leading to alterations in chromatin remodeling and enhanced gene transcription. | ||||||
Ellagic Acid, Dihydrate | 476-66-4 | sc-202598 sc-202598A sc-202598B sc-202598C | 500 mg 5 g 25 g 100 g | $58.00 $95.00 $245.00 $727.00 | 8 | |
Ellagic acid, a polyphenolic compound found in various fruits and nuts, activates WDR40A by modulating various signaling pathways, including NF-κB and PI3K/Akt, leading to enhanced transcriptional activity and gene expression associated with WDR40A. | ||||||
Berberine | 2086-83-1 | sc-507337 | 250 mg | $92.00 | 1 | |
Berberine, an isoquinoline alkaloid found in several plants, activates WDR40A indirectly by modulating signaling pathways such as AMPK and NF-κB, which influence gene expression patterns and transcriptional activity associated with WDR40A. | ||||||