VPS13A Inhibitors
VPS13A inhibitors comprise a diverse repertoire of chemicals targeting various cellular processes and signaling pathways intricately linked to VPS13A-mediated membrane dynamics. Latrunculin A disrupts actin polymerization, altering cytoskeletal dynamics and influencing VPS13A-mediated membrane transport processes. Y-27632, a ROCK inhibitor, modulates actin cytoskeleton, perturbing cellular structures governed by VPS13A-related membrane dynamics. Brefeldin A, an ARF activator, disrupts membrane trafficking, impacting vesicular transport and cellular structures associated with VPS13A-mediated membrane dynamics. CK-666, an Arp2/3 complex inhibitor, perturbs actin polymerization, influencing VPS13A-related membrane trafficking and cytoskeletal dynamics. NSC 23766, a Rac1 inhibitor, modulates cytoskeletal dynamics, altering cellular structures associated with VPS13A-mediated transport and membrane dynamics regulated by Rac1.
Furthermore, Dynasore disrupts clathrin-mediated endocytosis, influencing endocytic pathways and cellular processes governed by VPS13A-related membrane trafficking. Cytochalasin D, an actin polymerization inhibitor, alters cytoskeletal dynamics, impacting membrane trafficking processes and cellular structures associated with VPS13A-mediated transport. CK-869, an Arp2/3 complex inhibitor, perturbs actin polymerization, influencing VPS13A-related membrane trafficking and cytoskeletal dynamics. Additionally, Jaspisinolide, an actin polymerization inducer, influences cytoskeletal dynamics, altering membrane trafficking processes and cellular structures associated with VPS13A-mediated transport. GGTI-2418, a GGTase I inhibitor, modulates membrane trafficking, impacting prenylation pathways and cellular processes governed by VPS13A-related membrane dynamics. SMIFH2, a formin inhibitor, modulates actin cytoskeleton, perturbing cellular structures associated with VPS13A-mediated membrane trafficking. Moreover, ML141, a Cdc42 inhibitor, influences cytoskeletal dynamics, altering cellular structures associated with VPS13A-mediated transport and membrane dynamics regulated by Cdc42. This array of inhibitors provides valuable tools for dissecting the intricate regulatory networks involving VPS13A, paving the way for precise experimental investigations.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Latrunculin A, Latrunculia magnifica | 76343-93-6 | sc-202691 sc-202691B | 100 µg 500 µg | $260.00 $799.00 | 36 | |
Latrunculin A, an actin polymerization inhibitor, disrupts cytoskeletal dynamics. Its impact on actin dynamics indirectly influences VPS13A by altering membrane trafficking processes and cellular structures associated with VPS13A-mediated transport. | ||||||
Y-27632, free base | 146986-50-7 | sc-3536 sc-3536A | 5 mg 50 mg | $182.00 $693.00 | 88 | |
Y-27632, a Rho-associated protein kinase (ROCK) inhibitor, modulates actin cytoskeleton. Its influence on ROCK-mediated signaling indirectly affects VPS13A by perturbing cytoskeletal organization and cellular processes governed by VPS13A-related membrane dynamics. | ||||||
Brefeldin A | 20350-15-6 | sc-200861C sc-200861 sc-200861A sc-200861B | 1 mg 5 mg 25 mg 100 mg | $30.00 $52.00 $122.00 $367.00 | 25 | |
Brefeldin A, an ADP-ribosylation factor (ARF) activator, disrupts membrane trafficking. Its impact on ARF-mediated processes indirectly influences VPS13A by altering vesicular transport and the cellular structures associated with VPS13A-mediated membrane dynamics. | ||||||
CK 666 | 442633-00-3 | sc-361151 sc-361151A | 10 mg 50 mg | $315.00 $1020.00 | 5 | |
CK-666, an Arp2/3 complex inhibitor, disrupts actin polymerization. Its influence on Arp2/3-mediated processes indirectly affects VPS13A by perturbing actin dynamics and cellular processes governed by VPS13A-related membrane trafficking. | ||||||
Dynamin Inhibitor I, Dynasore | 304448-55-3 | sc-202592 | 10 mg | $87.00 | 44 | |
Dynasore, a dynamin inhibitor, disrupts clathrin-mediated endocytosis. Its influence on dynamin-mediated processes indirectly affects VPS13A by perturbing endocytic pathways and cellular processes governed by VPS13A-related membrane trafficking. | ||||||
Cytochalasin D | 22144-77-0 | sc-201442 sc-201442A | 1 mg 5 mg | $145.00 $442.00 | 64 | |
Cytochalasin D, an actin polymerization inhibitor, disrupts cytoskeletal dynamics. Its impact on actin dynamics indirectly influences VPS13A by altering membrane trafficking processes and cellular structures associated with VPS13A-mediated transport. | ||||||
CK-869 | 388592-44-7 | sc-507274 | 5 mg | $160.00 | ||
CK-869, an Arp2/3 complex inhibitor, disrupts actin polymerization. Its influence on Arp2/3-mediated processes indirectly affects VPS13A by perturbing actin dynamics and cellular processes governed by VPS13A-related membrane trafficking. | ||||||
SMIFH2 | 340316-62-3 | sc-507273 | 5 mg | $140.00 | ||
SMIFH2, a formin inhibitor, modulates actin cytoskeleton. Its impact on formin-mediated processes indirectly influences VPS13A by altering actin dynamics and cellular structures associated with VPS13A-mediated membrane trafficking. | ||||||
ML 141 | 71203-35-5 | sc-362768 sc-362768A | 5 mg 25 mg | $134.00 $502.00 | 7 | |
ML141, a Cdc42 inhibitor, modulates cytoskeletal dynamics. Its influence on Cdc42-mediated signaling indirectly affects VPS13A by perturbing cellular structures associated with VPS13A-mediated transport and membrane dynamics regulated by Cdc42. | ||||||