Varicella Zoster Virus IV inhibitors are a specialized class of chemical compounds designed to target and inhibit the activity of the Varicella Zoster Virus (VZV), particularly focusing on its type IV functions. The Varicella Zoster Virus, a member of the Herpesviridae family, is responsible for conditions such as chickenpox and shingles. Its replication and spread within the host are facilitated by a series of viral proteins and enzymes that are critical for its life cycle. VZV IV inhibitors aim to disrupt these essential viral processes to understand better the dynamics of VZV infection and replication.
These inhibitors work by specifically binding to and interfering with the viral proteins or enzymes associated with VZV type IV functions. This interaction prevents the virus from carrying out necessary steps in its replication cycle, such as nucleic acid synthesis, protein processing, or assembly of new viral particles. By blocking these interactions, VZV IV inhibitors help elucidate the role of specific viral components in the infection process. Researchers use these inhibitors to study the mechanisms underlying VZV pathogenesis, aiming to gain insights into how the virus propagates and how its life cycle can be disrupted at various stages. The detailed understanding of these mechanisms contributes to a broader comprehension of VZV biology and its impact on host cells.
SEE ALSO...
| Product Name | CAS # | Catalog # | QUANTITY | Price | Citations | RATING |
|---|---|---|---|---|---|---|
Acyclovir | 59277-89-3 | sc-202906 sc-202906A | 50 mg 500 mg | $150.00 $940.00 | 2 | |
Nucleoside analogue that gets incorporated into the viral DNA during replication, leading to chain termination and cessation of viral replication. | ||||||
Valacyclovir Hydrochloride | 124832-27-5 | sc-204937 sc-204937A | 50 mg 100 mg | $119.00 $153.00 | ||
Prodrug of Acyclovir; upon metabolism, it converts to Acyclovir in the body, inhibiting viral DNA replication as mentioned above. | ||||||
Famciclovir | 104227-87-4 | sc-211498 | 100 mg | $123.00 | ||
Prodrug that gets metabolized to Penciclovir in the body. Penciclovir acts similarly to Acyclovir, inhibiting viral DNA replication by chain termination. | ||||||
Penciclovir | 39809-25-1 | sc-203183 | 100 mg | $260.00 | ||
Nucleoside analogue that gets incorporated into the viral DNA, inhibiting viral replication through chain termination. | ||||||
Foscarnet sodium | 63585-09-1 | sc-205330 sc-205330A | 1 g 5 g | $190.00 $676.00 | ||
Direct inhibitor of viral DNA polymerase without requiring activation by viral kinase. It disrupts the pyrophosphate-binding site, thus inhibiting viral replication. | ||||||
Cidofovir | 113852-37-2 | sc-482141 | 50 mg | $135.00 | ||
Nucleotide analogue that inhibits VZV DNA polymerase, leading to reduced viral DNA synthesis and replication. | ||||||
Brivudine | 69304-47-8 | sc-205607 sc-205607A sc-205607B sc-205607C | 10 mg 25 mg 100 mg 1 g | $224.00 $469.00 $1020.00 $2142.00 | 4 | |
Thymidine nucleoside analogue, inhibits viral DNA synthesis once it gets incorporated into the growing DNA chain. | ||||||
Ganciclovir | 82410-32-0 | sc-203963 sc-203963A | 50 mg 250 mg | $233.00 $421.00 | 1 | |
Nucleoside analogue, primarily used against CMV but has some activity against VZV. It gets incorporated into viral DNA and leads to premature chain termination, inhibiting replication. | ||||||
Vidarabine Monohydrate | 24356-66-9 | sc-296694 | 1 g | $199.00 | ||
Purine nucleoside analogue, inhibits DNA synthesis in herpesviruses, including VZV, by terminating the growing viral DNA chain. | ||||||
Trifluorothymidine | 70-00-8 | sc-222370 sc-222370A | 100 mg 1 g | $179.00 $500.00 | 1 | |
Fluorinated pyrimidine nucleoside analogue, gets incorporated into viral DNA, causing defective DNA synthesis in VZV. | ||||||